ArticleScientific reports2019
Effects of Different Diets on Microbiota in The Small Intestine Mucus and Weight Regulation in Rats.
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Evaluating the Correlation Between Fecal Microbiota Profiles and Clinical Presentation in Pediatric Patients with Celiac Disease.Middle East journal of digestive diseases · 2025Article
- Gut Microbiota, Bacterial Translocation, and Stroke: Current Knowledge and Future Directions.Biomedicines · 2024Review
- Role of the Small Intestinal Microbiota in Gastrointestinal Disorders.The Korean journal of helicobacter and upper gastrointestinal research · 2024Review
- Distinctive duodenal microbiomes and bile acid profiles in duodenal tumor patients revealed by prospective observational study.Scientific reports · 2024Observational
- Resident gut microbiota community determines the efficacy of soluble fiber in reducing adiposity.Frontiers in microbiology · 2024Article
- Comparing Transgenic Production to Supplementation of ω-3 PUFA Reveals Distinct But Overlapping Mechanisms Underlying Protection Against Metabolic and Hepatic Disorders.Function (Oxford, England) · 2023Article
- Lactase bacteria in intestinal mucosa are associated with diarrhea caused by high-fat and high-protein diet.BMC microbiology · 2022Article
- Gut Mucosal Microbiome Is Perturbed in Rheumatoid Arthritis Mice and Partly Restored after TDAG8 Deficiency or Suppression by Salicylanilide Derivative.International journal of molecular sciences · 2022Article
- Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice.Particle and fibre toxicology · 2022Article
- Influence of the gut microbiome on inflammatory and immune response after stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2021Review
- Effect of a High-Fat Diet on the Small-Intestinal Environment and Mucosal Integrity in the Gut-Liver Axis.Cells · 2021Article
- Review
- Maintaining Digestive Health in Diabetes: The Role of the Gut Microbiome and the Challenge of Functional Foods.Microorganisms · 2021Review
- Review
- Metabolomics analysis of plasma and adipose tissue samples from mice orally administered with polydextrose and correlations with cecal microbiota.Scientific reports · 2020Article
- Review
- Analysis of Human Faecal Host Proteins: Responsiveness to 10-Week Dietary Intervention Modifying Dietary Protein Intake in Elderly Males.Frontiers in nutrition · 2020Article
- The Beta-Diversity ofFrontiers in microbiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While the microbial community of the small intestine mucus (SIM) may also play a role in human health maintenance and disease genesis, it has not been extensively profiled and whether it changes with diet is still unclear. To investigate the flora composition of SIM and the effects of diet on it, we fed SD rats for 12 weeks with standard diet (STD), high-fat diet (HFD), high-sugar diet (HSD) and high-protein diet (HPD), respectively. After 12 weeks, the rats were sacrificed, SIM and stool samples were collected, and high-throughput 16S rRNA gene sequencing was used to analyze the microbiota. We found that fecal microbiota (FM) was dominated by Firmicutes and Bacteroidetes, while in SIM, Firmicutes and Proteobacteria were the two most abundant phyla and the level of Bacteroidetes dramatically decreased. The microbiota diversity of SIM was less than that of feces. The community composition of SIM varied greatly with different diets, while the composition of FM altered little with different diets. The relative abundance of Bacteroidetes and Allobaculum in SIM were negatively correlated with weight gain. There was no significant correlation between FM and weight gain. In conclusion, the community profile of SIM is different from that of feces and susceptible to diet.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.