Evidence map›Paper›PMID 31186482›Full record

ArticleScientific reports2019

Association of antidepressants with brain morphology in early stages of psychosis: an imaging genomics approach.

Oleg Bykowsky, Fabienne Harrisberger, André Schmidt, Renata Smieskova, Daniel J Hauke, Laura Egloff, Anita Riecher-Rössler, Paolo Fusar-Poli, Christian G Huber, Undine E Lang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 4 countries.

Oleg BykowskyNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Fabienne HarrisbergerNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
André SchmidtNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Renata SmieskovaNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Daniel J HaukeNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Laura EgloffNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland.
Anita Riecher-RösslerPsychiatric University Hospital (UPK), University of Basel, Basel, Switzerland.
Paolo Fusar-PoliEarly Psychosis: Interventions and Clinical Detection (EPIC) lab, Department of Psychosis Studies, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.
Christian G HuberPsychiatric University Hospital (UPK), University of Basel, Basel, Switzerland.ORCID http://orcid.org/0000-0002-2246-9008
Undine E LangPsychiatric University Hospital (UPK), University of Basel, Basel, Switzerland.
Christina AndreouPsychiatric University Hospital (UPK), University of Basel, Basel, Switzerland.
Stefan BorgwardtNeuropsychiatry and Brain Imaging, Department of Psychiatry (UPK), University of Basel, Basel, Switzerland. stefan.borgwardt@upkbs.ch.ORCID http://orcid.org/0000-0002-5792-3987
University of Basel · CHKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depressive symptoms in subjects at Clinical High Risk for Psychosis (CHR-P) or at first-episode psychosis (FEP) are often treated with antidepressants. Our cross-sectional study investigated whether brain morphology is altered by antidepressant medication. High-resolution T

Indexed as

GenomicsAdultAntidepressive AgentsBrainCerebral CortexFemaleHumansLinear ModelsMalePsychotic DisordersSchizophreniaAntidepressive Agents

Identifiers

PMID31186482
PMCPMC6560086
OpenAlexW2952009810

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.