SynthesisCritical care (London, England)2019
Prevalence of post-traumatic stress disorder symptoms in adult critical care survivors: a systematic review and meta-analysis.
Synthesis in Critical care (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 15 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
135 citing papers in PubMed, 15 syntheses or guidelines pooled it, 294 citations in OpenAlex.
- Pooled it
- Efficacy of virtual reality-based exposure therapy for post-traumatic stress disorder in military veterans: a systematic review and meta-analysis.Frontiers in psychiatry · 2026Pooled it
- [S3 guideline on sepsis-prevention, diagnosis, therapy, and follow-up care-update 2025].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2025Guideline
- Leprosy relapse after multidrug therapy: Systematic review and meta-analysis.PLoS neglected tropical diseases · 2025Pooled it
- Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children.The Cochrane database of systematic reviews · 2025Pooled it
- Global prevalence of post-COVID-19 condition: a systematic review and meta-analysis of prospective evidence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2025Pooled it
- Impact of preoperative uni- or multimodal prehabilitation on postoperative morbidity: meta-analysis.BJS open · 2023Pooled it
- Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023Pooled it
- What is known about the prevalence of household food insecurity in Canada during the COVID-19 pandemic: a systematic review.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2022Pooled it
- Nursing interventions to cover patients' basic needs in the intensive care context - A systematic review.Nursing open · 2022Pooled it
- Conducting proportional meta-analysis in different types of systematic reviews: a guide for synthesisers of evidence.BMC medical research methodology · 2021Pooled it
- Lifetime prevalence of suicidal ideation and suicidal behaviors in gender non-conforming youths: a meta-analysis.European child & adolescent psychiatry · 2021Pooled it
- Prevalence of post-traumatic stress symptoms among people influenced by coronavirus disease 2019 outbreak: A meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2021Pooled it
- The prevalence of PTSS under the influence of public health emergencies in last two decades: A systematic review and meta-analysis.Clinical psychology review · 2021Pooled it
- Infectious Disease Outbreak and Post-Traumatic Stress Symptoms: A Systematic Review and Meta-Analysis.Frontiers in psychology · 2021Pooled it
- Effects of a brief primary care intervention for post-traumatic stress disorder symptoms after critical illness on health-related quality of life - A secondary analysis of the PICTURE randomised controlled trial.The European journal of general practice · 2026Trial
- Depressive symptoms are a key determinant of health-related quality of life in ICU survivors with psychological distress.Scientific reports · 2026Trial
- A randomized clinical trial to evaluate the effect of post-intensive care multidisciplinary consultations on mortality and the quality of life at 1 year.Intensive care medicine · 2024Trial
- Effect of Dexmedetomidine on Posttraumatic Stress Disorder in Patients Undergoing Emergency Trauma Surgery: A Randomized Clinical Trial.JAMA network open · 2023Trial
- Trial
75 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAs more patients are surviving intensive care, mental health concerns in survivors have become a research priority. Among these, post-traumatic stress disorder (PTSD) can have an important impact on the quality of life of critical care survivors. However, data on its burden are conflicting. Therefore, this systematic review and meta-analysis aimed to evaluate the prevalence of PTSD symptoms in adult critical care patients after intensive care unit (ICU) discharge.
methodsWe searched MEDLINE, EMBASE, LILACS, Web of Science, PsycNET, and Scopus databases from inception to September 2018. We included observational studies assessing the prevalence of PTSD symptoms in adult critical care survivors. Two reviewers independently screened studies and extracted data. Studies were meta-analyzed using a random-effects model to estimate PTSD symptom prevalence at different time points, also estimating confidence and prediction intervals. Subgroup and meta-regression analyses were performed to explore heterogeneity. Risk of bias was assessed using the Joanna Briggs Institute tool and the GRADE approach.
resultsOf 13,267 studies retrieved, 48 were included in this review. Overall prevalence of PTSD symptoms was 19.83% (95% confidence interval [CI], 16.72-23.13; I
conclusionPTSD symptoms may affect 1 in every 5 adult critical care survivors, with a high expected prevalence 12 months after discharge. ICU survivors should be screened for PTSD symptoms and cared for accordingly, given the potential negative impact of PTSD on quality of life. In addition, action should be taken to further explore the causal relationship between ICU stay and PTSD, as well as to propose early measures to prevent PTSD in this population.
trial registrationPROSPERO, CRD42017075124 , Registered 6 December 2017.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.