Evidence map›Paper›PMID 31186023›Full record

ArticleRadiation oncology (London, England)2019

Single isocenter stereotactic radiosurgery for patients with multiple brain metastases: dosimetric comparison of VMAT and a dedicated DCAT planning tool.

Jan Hofmaier, Raphael Bodensohn, Sylvia Garny, Indrawati Hadi, Daniel F Fleischmann, Michael Eder, Yavuz Dinc, Michael Reiner, Stefanie Corradini, Katia Parodi and 2 more

Abstract readComparative Study
In one paragraph

Article in Radiation oncology (London, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  5. Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026
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  16. Effect of different optimization parameters in single isocenter multiple brain metastases radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024
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  18. Impact of MLC error on dose distribution in SRS treatment of single-isocenter multiple brain metastases: comparison between DCAT and VMAT techniques.Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jan HofmaierDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany. jan.hofmaier@med.uni-muenchen.de.ORCID http://orcid.org/0000-0002-7936-9753
Raphael BodensohnDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Sylvia GarnyDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Indrawati HadiDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Daniel F FleischmannDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Michael EderDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Yavuz DincDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Michael ReinerDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Stefanie CorradiniDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Katia ParodiDepartment of Medical Physics, Faculty of Physics, LMU Munich, Munich, Germany.
Claus BelkaDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.
Maximilian NiyaziDepartment of Radiation Oncology, University Hospital, LMU Munich, Marchioninistraße 15, 81377, Munich, DE, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this dosimetric study, a dedicated planning tool for single isocenter stereotactic radiosurgery for multiple brain metastases using dynamic conformal arc therapy (DCAT) was compared to standard volumetric modulated arc therapy (VMAT).

methodsTwenty patients with a total of 66 lesions who were treated with the DCAT tool were included in this study. Single fraction doses of 15-20 Gy were prescribed to each lesion. Patients were re-planned using non-coplanar VMAT. Number of monitor units as well as V

resultsThe automated DCAT planning tool performed significantly better in terms of all investigated metrics (p < 0.05), in particular healthy brain sparing (V

conclusionsThe dedicated DCAT planning tool performed better than VMAT in terms of healthy brain sparing and treatment efficiency, in particular for nearly spherical lesions. In contrast, VMAT can be superior in cases with irregularly shaped lesions.

Indexed as

AlgorithmsAgedBrain NeoplasmsFemaleHumansMaleMiddle AgedNeoplasmsOrgans at RiskPrognosisRadiosurgeryRadiotherapy, ConformalRadiotherapy DosageRadiotherapy, Intensity-ModulatedRadiotherapy Planning, Computer-AssistedRetrospective StudiesBrain metastasesDynamic conformal arc therapySingle IsocenterStereotactic radiosurgeryVMAT

Identifiers

PMID31186023
PMCPMC6560766

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.