ArticleBMC urology2019
Testicular epidermoid cysts: a reevaluation.
Article in BMC urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 35 citations in OpenAlex.
- Multiparametric Ultrasound for Characterisation of Testicular Lesions: Beyond Orchiectomy.Diagnostics (Basel, Switzerland) · 2026Review
- A sound approach to stay on the ball-a review of scrotal pathologies on ultrasound imaging.The British journal of radiology · 2026Review
- Molecular pathology of testicular germ cell tumours: an update for practicing pathologists.Histopathology · 2026Review
- Clinical features and surgical outcomes of testicular epidermoid cysts in children.Pediatric surgery international · 2025Review
- Epidermoid cyst arising from the epididymis in a prepubertal boy.Urology case reports · 2025Article
- A rare finding of testicular epidermoid keratinized cyst in a prepubertal boy: case report and management standardization.Journal of ultrasound · 2025Article
- Monodermal teratoma: Three case reports and review of literature.World journal of clinical cases · 2024Article
- Epidermoid cyst of the testis: A report of three cases.Clinical case reports · 2024Article
- Extratesticular intrascrotal epidermoid cysts presenting like polyorchidism: a case report.The Pan African medical journal · 2024Article
- Epidermoid cyst discovered concomitant with torsion of the spermatic cord: A case report.SAGE open medical case reports · 2024Article
- Multiparametric Ultrasound for Diagnosing Testicular Lesions: Everything You Need to Know in Daily Clinical Practice.Cancers · 2023Review
- [Fundamentals in the pathology of testicular germ cell tumours].Pathologie (Heidelberg, Germany) · 2023Article
- Multiple scrotal and testicular epidermoid cysts: A rare case report.Radiology case reports · 2023Article
- [Diagnostic problems in testicular tumours in consultant pathology : A practical guide].Pathologie (Heidelberg, Germany) · 2022Review
- An Overview of the Role of Multiparametric MRI in the Investigation of Testicular Tumors.Cancers · 2022Review
- Testicular Epidermoid Cyst: A Rare Case Report.International journal of surgery case reports · 2022Article
- Intrascrotal Testicular and Extratesticular Epidermoid Cysts: About Two Cases.Journal of the Belgian Society of Radiology · 2022Article
- Review
- When to ask for an MRI of the scrotum.Andrology · 2021Review
- Cisplatin Resistance in Testicular Germ Cell Tumors: Current Challenges from Various Perspectives.Cancers · 2020Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTesticular epidermoid cysts (TECs) are rare benign testicular neoplasms. As TECs are rarely associated with germ cell tumours (GCTs), the understanding of biological behaviour and clinical management of TEC is unresolved.
methodsWe retrospectively searched the files of patients treated for testicular neoplasms and germ cell cancer in the time from 2000 to 2017. Those with TEC were subjected to closer review looking to clinical and histological features, and to results from imaging with ultrasonography (US), contrast enhanced sonography (CEUS) and magnetic resonance imaging (MRI).
resultsAmong 589 patients undergoing surgery for testicular tumour, nine simple TECs were identified (1.5, 95% confidence intervals 0.53-2.50%). Median age was 26 years. Imaging revealed sharply demarcated roundish lesions with avascular central areas. Eight patients underwent testis-sparing excision with no recurrence ensuing. One had orchiectomy because of large size of the mass. Histologically, TECs consisted of cornifying squamous cell epithelium and no accompanying germ cell neoplasia in situ. Two additional cases (0.3% of all) required orchiectomy because these TECs were associated with ipsilateral GCT.
conclusionsTEC is usually a benign lesion that can safely be diagnosed with US, CEUS and MRI due to its roundish shape and its avascular centre. Histologically, this TEC corresponds to the prepubertal-type teratoma unrelated to germ cell neoplasia in situ of the 2016 WHO classification. The other subtype of TEC that is associated with invasive GCT represents a teratoma of postpubertal-type. From a clinical point of view it could be easier to differentiate between a "simple TEC" which is benign (prepubertal type) and a "complex TEC" which is malignant because of its association with invasive GCT.
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