Evidence map›Paper›PMID 31185923›Full record

ArticleBMC geriatrics2019

Validity of a novel screen for cognitive impairment and neuropsychiatric symptoms in cardiac rehabilitation.

Dana Mohammad, Nathan Herrmann, Mahwesh Saleem, Richard H Swartz, Paul I Oh, Janelle Bradley, Parco Chan, Courtney Ellis, Krista L Lanctôt

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. PCSK9 Inhibition Reduces Depressive like Behavior in CUMS-Exposed Rats: Highlights on HMGB1/RAGE/TLR4 Pathway, NLRP3 Inflammasome Complex and IDO-1.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2023
    Article
  3. Cognition and Exercise: GENERAL OVERVIEW AND IMPLICATIONS FOR CARDIAC REHABILITATION.Journal of cardiopulmonary rehabilitation and prevention · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dana MohammadHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Nathan HerrmannHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Mahwesh SaleemHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Richard H SwartzHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Paul I OhUniversity Health Network at Toronto Rehabilitation Institute, Toronto, Ontario, Canada.
Janelle BradleyHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Parco ChanHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Courtney EllisDepartment of Kinesiology, University of Waterloo, Waterloo, Ontario, Canada.
Krista L LanctôtHurvitz Brain Sciences Program, Sunnybrook Research Institute, Toronto, Ontario, Canada. krista.lanctot@sunnybrook.ca.ORCID 0000-0001-7024-6637
Sunnybrook Health Science Centre · CAUniversity Health Network · CAUniversity of Waterloo · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCurrently, there is no composite screening tool that can efficiently and effectively assess prevalent yet under-recognized cognitive and neuropsychiatric comorbidities in patients with cardiovascular disease. We aimed to determine the validity and feasibility of a novel screen assessing cognitive impairment, anxiety, apathy and depression (CAAD screen) in those attending cardiac rehabilitation (CR).

methodsAll patients diagnosed with cardiovascular disease or cardiovascular risk factors entering CR were screened as part of clinical care. A subset of those patients agreed to complete validation assessments (n = 127). Screen results were compared to widely accepted standards for cognition, anxiety, apathy, and depression using a modified receiver operating characteristic (ROC) and area under the curve analysis.

resultsThe screen was completed by 97% of participants in 10 min or less with an average completion time of approximately 5 min. Screening scores adjusted for age, sex and years of education had acceptable or excellent validity compared to widely accepted standard diagnoses: CAAD-Cog (AUC = 0.80); CAAD-Anx (AUC = 0.81); CAAD-Apathy (AUC = 0.79) and CAAD-Dep (AUC = 0.85).

conclusionsThe CAAD screen may be a valid and feasible tool for detecting cognitive impairment, anxiety, apathy and depression in CR settings.

Indexed as

Cardiac RehabilitationNeuropsychological TestsAgedCanadaCardiovascular DiseasesCognitionCognitive DysfunctionComorbidityEmotionsFemaleHumansMaleMass ScreeningMiddle AgedAnxietyApathyCardiac rehabilitationCognitionDepressionScreen

Identifiers

PMID31185923
PMCPMC6558737
OpenAlexW2949685361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.