ArticleJournal of the American Heart Association2019
Association of Major Adverse Cardiac Events up to 5 Years in Patients With Chest Pain Without Significant Coronary Artery Disease in the Korean Population.
Article in Journal of the American Heart Association, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04736212 (Assessment of Breathing Using an Under-bed Weighing Scale), which is not on this map. Cited by 43 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Breathing Using an Under-bed Weighing Scale
Who cites it
43 citing papers in PubMed, 4 syntheses or guidelines pooled it, 76 citations in OpenAlex.
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- Impact of complete versus culprit-only revascularization on major adverse cardiovascular event in diverse subpopulations.Future cardiology · 2024Pooled it
- Pooled it
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- Bilateral versus single internal mammary artery use in patients with chronic kidney disease.General thoracic and cardiovascular surgery · 2026Article
- Comparative analysis of quality of life post coronary angioplasty and bypass surgery: A follow-up study on cardiac patients.Medicine · 2026Article
- Cumulative Serum Endothelin-1 and Endothelin-3 Level Predicts 1-year Adverse Cardiac Events after ST-Elevation Acute Myocardial Infarction.The International journal of angiology : official publication of the International College of Angiology, Inc · 2026Article
- Impact of bilateral internal mammary artery grafting in patients with mildly decreased renal function.General thoracic and cardiovascular surgery · 2026Article
- The role of MAFLD in predicting major adverse cardiovascular events in patients with stable COPD: a prospective cohort study.Frontiers in medicine · 2026Article
- Impact of Arteriovenous Access Formation on Cardiac Structure and Function in Hemodialysis Patients.Annals of vascular diseases · 2026Article
- Opioids in Critically Ill Acute Myocardial Infarction Patients: A Retrospective Analysis of the MIMIC-IV Database.Journal of general internal medicine · 2025Article
- Framingham risk score is a useful indicator of posttransplant cardiovascular events and survival among Korean kidney transplant recipients: a nationwide, prospective cohort study.Kidney research and clinical practice · 2025Article
- Comparative validation of the Mayo Clinic imaging classification and PROPKD score for predicting ADPKD progression across diverse ethnic cohorts.Journal of nephrology · 2025Article
- Comparative safety of biologic and targeted synthetic disease-modifying anti-rheumatic drugs for cardiovascular outcomes in rheumatoid arthritis.Rheumatology (Oxford, England) · 2025Article
- Composite socio-environmental risk score for cardiovascular assessment: An explainable machine learning approach.American journal of preventive cardiology · 2025Article
- The association between dietary diversity score and food insecurity and novel cardiovascular risk factors in type 2 diabetes mellitus patients: a cross-sectional study.Journal of diabetes and metabolic disorders · 2025Article
- Clinical implications and pharmacological considerations of glycemic variability in patients with type 2 diabetes mellitus.Scientific reports · 2024Article
- Sex-specific association of cardiovascular drug doses with adverse outcomes in atrial fibrillation.Open heart · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Significant coronary artery disease has a well-known association with long-term adverse cardiovascular events. In this study, we aimed to evaluate its association with long-term major adverse clinical events ( MACE ) up to 5 years in patients who presented with chest pain without significant coronary artery disease . Methods and Results A total of 5890 subjects with chest pain without significant coronary artery disease were prospectively enrolled in this study. The mean follow-up duration was 3.4 years. Multivariable Cox proportional hazards regression analysis was performed for assessing the independent risk factors for MACE or sustained angina pectoris. MACE was defined as the composite of total death, myocardial infarction, coronary revascularization, stroke, and hospitalization because of heart failure. Ninety-one (2.2%) patients developed MACE , and 309 (8.1%) patients developed sustained angina pectoris , both within 5 years. In multivariable Cox proportional hazards regression analysis, the risk of MACE was significantly associated with age (per 5 years; hazard ratio [ HR ], 1.44; 95% CI , 1.30-1.60) and insignificant coronary stenosis (30%-70%; HR, 2.03; 95% CI; 1.28-3.21). The risk of sustained angina pectoris was significantly associated with age (per 5 years; HR, 1.05; 95% CI, 1.01-1.11), dyslipidemia ( HR, 1.34; 95% CI , 1.06-1.70), insignificant coronary stenosis ( HR, 2.54; 95% CI , 1.94-3.31), coronary artery spasm (HR, 1.42; 95% CI , 1.11-1.80), and myocardial bridge (HR, 1.37; 95% CI , 1.04-1.81). Conclusions In patients without significant CAD , aging and insignificant coronary stenosis have a strong association with future long-term MACE . Also, aging, dyslipidemia, insignificant coronary stenosis , coronary artery spasm, and myocardial bridge are strongly associated with future angina pectoris .
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