Evidence map›Paper›PMID 31185758›Full record

ArticleExpert opinion on drug metabolism & toxicology2019

Ritonavir and cobicistat as pharmacokinetic enhancers in pregnant women.

Ahizechukwu C Eke, Mark Mirochnick

Open access · greenAbstract readEditorial
In one paragraph

Article in Expert opinion on drug metabolism & toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Fosamprenavir with Ritonavir Pharmacokinetics during Pregnancy.Antimicrobial agents and chemotherapy · 2020
    Trial
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Darunavir Pharmacokinetics With an Increased Dose During Pregnancy.Journal of acquired immune deficiency syndromes (1999) · 2020
    Article
  11. Tenofovir alafenamide use in pregnant and lactating women living with HIV.Expert opinion on drug metabolism & toxicology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Ahizechukwu C Ekea Division of Maternal Fetal Medicine & Clinical Pharmacology, Department of Gynecology & Obstetrics , Johns Hopkins University School of Medicine , Baltimore , MD , USA.
Mark Mirochnickc Division of Neonatology, Department of Pediatrics , Boston University School of Medicine , Boston , MA , USA.
Boston University · USJohns Hopkins Medicine · US

Funding

Clinical Pharmacology Training ProgramT32GM066691 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Matthew Michael Ippolito · 2003 to 2026
$6.4M
NIGMS NIH HHS T32 GM066691
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-HIV AgentsCobicistatDrug InteractionsDrug Therapy, CombinationFemaleHIV InfectionsHumansPregnancyPregnancy Complications, InfectiousRitonavirAnti-HIV AgentsCobicistatRitonavircobicistatPharmacoenhancerspregnancyritonavir

Identifiers

PMID31185758
PMCPMC9210948
OpenAlexW2950988410

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.