Evidence map›Paper›PMID 31185698›Full record

ArticleFoods (Basel, Switzerland)2019

Comparative Analysis of Lycopene Content from Different Tomato-Based Food Products on the Cellular Activity of Prostate Cancer Cell Lines.

Nathalia da Costa Pereira Soares, Monique de Barros Elias, Clara Lima Machado, Bruno Boquimpani Trindade, Radovan Borojevic, Anderson Junger Teodoro

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. The role of nutritional interventions in prostate cancer: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2021
    Review
  10. Transcription of lncRNARNA biology · 2020
    Article
  11. Broccoli (Foods (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Nathalia da Costa Pereira SoaresFood Science Department, Chemistry Institute, Universidade Federal do Rio de Janeiro (UFRJ), Avenida Athos da Silveira Ramos 149-Cidade Universitária, Rio de Janeiro 21941-909, Brazil. ncpsoares@gmail.com.
Monique de Barros EliasNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. moniquebarros.nutri@gmail.com.
Clara Lima MachadoNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. claramachado55@gmail.com.
Bruno Boquimpani TrindadeNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. bboquimpani@gmail.com.
Radovan BorojevicRegenerative Medicine Centre, Faculdade de Medicina de Petrópólis (FASE), Avenida Barão do Rio Branco 1003-Petrópolis, Rio de Janeiro 25680-120, Brazil. rrborojevic@gmail.com.
Anderson Junger TeodoroNutritional Biochemistry Core, Laboratory of Functional Foods, Universidade Federal do Estado do Rio de Janeiro (UNIRIO), Avenida Pasteur 296-Urca, Rio de Janeiro 22290-240, Brazil. atteodoro@gmail.com.
Universidade Federal do Estado do Rio de Janeiro · BRFaculdade de Medicina de Petrópolis · BRUniversidade Federal do Rio de Janeiro · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 0001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010.000174/2016 / E-26/010.002538/2016
6 · The paper itself

Abstract

Lycopene is more bioavailable in processed tomato products than in raw tomatoes, since arrangement of cis-isomers of lycopene during food processing and storage may increase its biological activity. The aim of the study is evaluate the influence of lycopene content from different tomato-based food products (extract, paste, ketchup and sauce) on cell proliferation, cell cycle, and rate of apoptosis of human prostate cancer cell lines. DU-145 and PC-3 cell lines were treated with lycopene content from different tomato-based food products (500-5000 μg/mL) for 96 h. The data showed a decrease in cell viability in both DU-145 and PC-3 cells after treatment with all lycopene extracts from tomato-based food products. Analysis of cell cycle revealed a decrease in the percentage of prostate cancer cells in G

Indexed as

bioactive compoundschemopreventionlycopeneprostate cancertomato-based food products

Identifiers

PMID31185698
PMCPMC6617171
OpenAlexW2951809906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.