Evidence map›Paper›PMID 31185644›Full record

ArticleMaterials (Basel, Switzerland)2019

Effect of Chitin Nanofibrils on Biocompatibility and Bioactivity of the Chitosan-Based Composite Film Matrix Intended for Tissue Engineering.

Natalia V Smirnova, Konstantin A Kolbe, Elena N Dresvyanina, Sergey F Grebennikov, Irina P Dobrovolskaya, Vladimir E Yudin, Thomas Luxbacher, Pierfrancesco Morganti

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natalia V SmirnovaInstitute of Macromolecular Compounds, Russian Academy of Sciences, V.O. Bolshoi pr. 31, 199004 St. Petersburg, Russia. nvsmirnoff@yandex.ru.
Konstantin A KolbeInstitute of Macromolecular Compounds, Russian Academy of Sciences, V.O. Bolshoi pr. 31, 199004 St. Petersburg, Russia. kkolbe@yandex.ru.
Elena N DresvyaninaSaint-Petersburg State University of Industrial Technologies and Design, ul. Bolšaja Morskaja 18, 191183 St. Petersburg, Russia. elenadresvyanina@gmail.com.
Sergey F GrebennikovSaint-Petersburg State University of Industrial Technologies and Design, ul. Bolšaja Morskaja 18, 191183 St. Petersburg, Russia. grebennikovsf@gmail.com.
Irina P DobrovolskayaInstitute of Macromolecular Compounds, Russian Academy of Sciences, V.O. Bolshoi pr. 31, 199004 St. Petersburg, Russia. dobrov@hq.macro.ru.
Vladimir E YudinInstitute of Macromolecular Compounds, Russian Academy of Sciences, V.O. Bolshoi pr. 31, 199004 St. Petersburg, Russia. yudin@hq.macro.ru.
Thomas LuxbacherAnton Paar GmbH, Anton-Paar-Str. 20, 8054 Graz, Austria. thomas.luxbacher@anton-paar.com.
Pierfrancesco MorgantiDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", Via L. De Crecchio 7, 80138 Naples, Italy. pierfrancesco.morganti@mavicosmetics.it.

Funding

Russian Science Foundation 19-73-30003
6 · The paper itself

Abstract

This paper discusses the mechanical and physicochemical properties of film matrices based on chitosan, as well as the possibility of optimizing these properties by adding chitin nanofibrils. It is shown that with the introduction of chitin nanofibrils as a filler, the mechanical stability of the composite materials increases. By varying the concentration of chitin nanofibrils, it is possible to obtain a spectrum of samples with different bioactive properties for the growth of human dermal fibroblasts. Film matrices based on the nanocomposite of chitosan and 5 wt % chitin nanofibrils have an optimal balance of mechanical and physicochemical properties and bioactivity in relation to the culture of human dermal fibroblasts.

Indexed as

chitin nanofibrilschitosancomposite matrixtissue engineering

Identifiers

PMID31185644
PMCPMC6600941

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.