Evidence map›Paper›PMID 31185643›Full record

ArticleInternational journal of molecular sciences2019

Assessment of the Antiangiogenic and Anti-Inflammatory Properties of a Maslinic Acid Derivative and its Potentiation using Zinc Chloride.

Ioana Zinuca Pavel, Rene Csuk, Corina Danciu, Stefana Avram, Flavia Baderca, Andreea Cioca, Elena-Alina Moacă, Ciprian-Valentin Mihali, Iulia Pinzaru, Danina Mirela Muntean and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Comparative Analysis ofPlants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ioana Zinuca PavelDepartment of Pharmacognosy, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. ioanaz.pavel@umft.ro.ORCID 0000-0002-2223-5228
Rene CsukDepartment of Organic Chemistry, Martin-Luther University Halle-Wittenberg, Kurt-Mothes-Str. 2, D-06120 Halle (Saale), Germany. rene.csuk@chemie.uni-halle.de.ORCID 0000-0001-7911-290X
Corina DanciuDepartment of Pharmacognosy, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. corina.danciu@umft.ro.
Stefana AvramDepartment of Pharmacognosy, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. stefana.avram@umft.ro.
Flavia BadercaDepartment of Microscopic Morphology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. baderca.flavia@umft.ro.ORCID 0000-0002-5755-179X
Andreea CiocaDepartment of Pathology, CFR Clinical Hospital, 13-15, Tudor Vladimirescu, Timişoara 300173, Romania. cioca.andreea19@gmail.com.
Elena-Alina MoacăDepartment of Toxicology, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. alina.moaca@umft.ro.ORCID 0000-0002-2631-7028
Ciprian-Valentin Mihali"George Emil Palade" Electron Microscopy Center, Institute of Life Sciences, Faculty of Medicine, "Vasile Goldiș" Western University of Arad, 86, Liviu Rebreanu St., Arad 310414, Romania. mihaliciprian@uvvg.ro.
Iulia PinzaruDepartment of Toxicology, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. iuliapinzaru@umft.ro.ORCID 0000-0003-2295-1926
Danina Mirela MunteanDepartment of Functional Sciences - Pathophysiology, Faculty of Medicine, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. daninamuntean@umft.ro.
Cristina Adriana DeheleanDepartment of Toxicology, Faculty of Pharmacy, "Victor Babeş" University of Medicine and Pharmacy, 2, Eftimie Murgu Sq., Timişoara 300041, Romania. cadehelean@umft.ro.
Victor Babeș University of Medicine and Pharmacy Timișoara · ROMartin Luther University Halle-Wittenberg · DEVasile Goldis Western University of Arad · RO

Funding

"Victor Babes" University of Medicine and Pharmacy of Timisoara "Victor Babes" University of Medicine and Pharmacy of Timisoara
6 · The paper itself

Abstract

Maslinic acid is a pentacyclic triterpene with a plethora of biological activities, including anti-inflammatory, antioxidant, antimicrobial, cardioprotective, and antitumor effects. New derivatives with improved properties and broad-spectrum activity can be obtained following structural changes of the compound. The present study was aimed to characterize a benzylamide derivative of maslinic acid-benzyl (2α, 3β) 2,3-diacetoxy-olean

Indexed as

Angiogenesis InhibitorsAnimalsAnti-Inflammatory AgentsChick EmbryoChloridesChorioallantoic MembraneDrug Therapy, CombinationFemaleMiceOleanolic AcidOtitisTriterpenesZinc CompoundsAngiogenesis InhibitorsAnti-Inflammatory AgentsChloridesmaslinic acidOleanolic AcidTriterpeneszinc chlorideZinc CompoundsangiogenesisEM2, benzylamide derivativeinflammationmaslinic acidzinc chloride

Identifiers

PMID31185643
PMCPMC6600266
OpenAlexW2948413628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.