Evidence map›Paper›PMID 31185612›Full record

ArticlePharmaceutics2019

In Vitro Evaluation of Eudragit Matrices for Oral Delivery of BCG Vaccine to Animals.

Imran Saleem, Allan G A Coombes, Mark A Chambers

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

Imran SaleemSchool of Pharmacy and Biomolecular Sciences, Liverpool John Moores University, Byrom Street, Liverpool L3 3AF, UK. I.Saleem@ljmu.ac.uk.ORCID 0000-0003-2382-6668
Allan G A CoombesPharmacy Australia Centre of Excellence, University of Queensland, School of Pharmacy, 20 Cornwall Street, Woolloongaba, QLD 4102, Australia. allancoombes1@gmail.com.
Mark A ChambersDepartment of Bacteriology, Animal and Plant Health Agency, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB, UK. mark.chambers@apha.gov.uk.ORCID 0000-0002-8073-8069
Animal and Plant Health Agency · GBLiverpool John Moores University · GBThe University of Queensland · AU

Funding

Department for Environment, Food and Rural Affairs SE3246
6 · The paper itself

Abstract

Bacillus Calmette-Guérin (BCG) vaccine is the only licensed vaccine against tuberculosis (TB) in humans and animals. It is most commonly administered parenterally, but oral delivery is highly advantageous for the immunisation of cattle and wildlife hosts of TB in particular. Since BCG is susceptible to inactivation in the gut, vaccine formulations were prepared from suspensions of Eudragit L100 copolymer powder and BCG in phosphate-buffered saline (PBS), containing Tween

Indexed as

BCGEudragitin vitro viabilityoral vaccinetuberculosis

Identifiers

PMID31185612
PMCPMC6630751
OpenAlexW2943714768

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.