Evidence map›Paper›PMID 31185601›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis and Cytostatic Effect of 3'-deoxy-3'-

Miklós Bege, Alexandra Kiss, Máté Kicsák, Ilona Bereczki, Viktória Baksa, Gábor Király, Gábor Szemán-Nagy, M Zsuzsa Szigeti, Pál Herczegh, Anikó Borbás

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Miklós BegeDepartment of Pharmaceutical Chemistry, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. bege.miklos@pharm.unideb.hu.
Alexandra KissDepartment of Biotechnology and Microbiology, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. kissalexandra0329@gmail.com.
Máté KicsákDepartment of Pharmaceutical Chemistry, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. kicsak.mate@pharm.unideb.hu.
Ilona BereczkiDepartment of Pharmaceutical Chemistry, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. bereczki.ilona@pharm.unideb.hu.
Viktória BaksaDepartment of Biotechnology and Microbiology, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. viktoriabaksa@gmail.com.
Gábor KirályDepartment of Biotechnology and Microbiology, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. kiru.eger@gmail.com.
Gábor Szemán-NagyDepartment of Biotechnology and Microbiology, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. mzsuzsa768@gmail.com.
M Zsuzsa SzigetiDepartment of Biotechnology and Microbiology, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. bigdegu@gmail.com.
Pál HerczeghDepartment of Pharmaceutical Chemistry, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. herczegh.pal@pharm.unideb.hu.
Anikó BorbásDepartment of Pharmaceutical Chemistry, University of Debrecen, 4032 Debrecen, Egyetem Tér 1, Hungary. borbas.aniko@pharm.unideb.hu.
University of Debrecen · HU

Funding

European Regional Development Fund GINOP-2.3.2-15-2016-00008, GINOP-2.3.3-15-2016-00021 and GINOP-2.3.3-15-2016-00004National Research, Development and Innovation Office of Hungary TÉT_15_IN-1-2016-0071 and K12880
6 · The paper itself

Abstract

A small library of 3'-deoxy-C3'-substituted xylofuranosyl-pyrimidine nucleoside analogues were prepared by photoinduced thiol-ene addition of various thiols, including normal and branched alkyl-, 2-hydroxyethyl, benzyl-, and sugar thiols, to 3'-exomethylene derivatives of 2',5'-di-

Indexed as

Molecular ConformationCarbon-13 Magnetic Resonance SpectroscopyCell LineCell NucleusCell ProliferationCell SurvivalCytostatic AgentsDimethyl SulfoxideHumansInhibitory Concentration 50NucleosidesProton Magnetic Resonance SpectroscopySulfhydryl CompoundsXyloseCytostatic AgentsDimethyl SulfoxideNucleosidesSulfhydryl CompoundsXylosecytostaticgenotoxicradical thiol-ene couplingsquamous carcinoma cell line (SCC)time-lapse imaging video-microscopyxylofuranosyl nucleoside

Identifiers

PMID31185601
PMCPMC6600393
OpenAlexW2946737880

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.