Evidence map›Paper›PMID 31184849›Full record

ArticleACS chemical biology2019

Small-Molecule Inhibition of the

Jesse A Jones, Allan M Prior, Ravi K R Marreddy, Rebecca D Wahrmund, Julian G Hurdle, Dianqing Sun, Kirk E Hevener

Abstract read
In one paragraph

Article in ACS chemical biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Antimicrobial agents and chemotherapy · 2024
    Article
  6. Article
  7. Mining Fatty Acid Biosynthesis for New Antimicrobials.Annual review of microbiology · 2022
    Review
  8. Expert opinion on therapeutic targets · 2021
    Article
  9. Application of Microbiome Management in Therapy forPathogens (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jesse A JonesDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Tennessee Health Science Center , Memphis , Tennessee 38163 , United States.ORCID 0000-0001-8006-5661
Allan M PriorDepartment of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy , University of Hawaii at Hilo , Hilo , Hawaii , 96720 , United States.ORCID 0000-0001-5650-4644
Ravi K R MarreddyCenter for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology , Texas A&M Health Science Center , Houston , Texas 77030 , United States.ORCID 0000-0003-0425-406X
Rebecca D WahrmundDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Tennessee Health Science Center , Memphis , Tennessee 38163 , United States.
Julian G HurdleCenter for Infectious and Inflammatory Diseases, Institute of Biosciences and Technology , Texas A&M Health Science Center , Houston , Texas 77030 , United States.ORCID 0000-0003-2214-8105
Dianqing SunDepartment of Pharmaceutical Sciences, The Daniel K. Inouye College of Pharmacy , University of Hawaii at Hilo , Hilo , Hawaii , 96720 , United States.ORCID 0000-0001-7330-1742
Kirk E HevenerDepartment of Pharmaceutical Sciences, College of Pharmacy , University of Tennessee Health Science Center , Memphis , Tennessee 38163 , United States.ORCID 0000-0002-5584-3625

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
Resource for Biocomputing Visualization and InformaticsP41GM103311 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2012 to 2017
$8.2M
Investigation of the FAS-II enzyme, FabK, as a druggable target for C. difficileR21AI126755 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HEVENER, KIRK EDWARD, HURDLE, JULIAN G · 2016 to 2017
$424k
NIAID NIH HHS R21 AI126755NIGMS NIH HHS P20 GM103466NIGMS NIH HHS P41 GM103311
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsClostridioides difficileClostridium InfectionsEnoyl-(Acyl-Carrier-Protein) Reductase (NADH)HumansImidazolesMolecular Docking SimulationSmall Molecule LibrariesStructure-Activity RelationshipAnti-Bacterial AgentsEnoyl-(Acyl-Carrier-Protein) Reductase (NADH)ImidazolesSmall Molecule Libraries

Identifiers

PMID31184849
PMCPMC6642025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.