Evidence map›Paper›PMID 31184522›Full record

ArticleRNA biology2019

microRNA-14 as an efficient suppressor to switch off ecdysone production after ecdysis in insects.

Kang He, Huamei Xiao, Yang Sun, Gongming Situ, Yu Xi, Fei Li

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. AZoological research · 2026
    Article
  3. Article
  4. Article
  5. Time-dependent changes in genome-wide gene expression and post-transcriptional regulation across the post-death process in silkworm.DNA research : an international journal for rapid publication of reports on genes and genomes · 2024
    Article
  6. Review
  7. The miRNAsInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Histone H3K27 methylation-mediated repression ofProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  12. Article
  13. Article
  14. Post-transcriptional regulation of insect metamorphosis and oogenesis.Cellular and molecular life sciences : CMLS · 2020
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Kang Hea Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insects, Zhejiang University , Hangzhou , China.ORCID 0000-0002-7270-8118
Huamei Xiaob College of Life Sciences and Resource Environment, Yichun University , Yichun , China.
Yang Sunc Department of Entomology, Nanjing Agricultural University , Nanjing , China.
Gongming Situc Department of Entomology, Nanjing Agricultural University , Nanjing , China.
Yu Xie Agricultural Genomes Institute at Shenzhen, Chinese Academy of Agricultural Sciences , Shenzhen , China.
Fei Lia Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insects, Zhejiang University , Hangzhou , China.ORCID 0000-0002-8410-5250
Nanjing Agricultural University · CNMinistry of Agriculture and Rural Affairs · CNAgricultural Genomics Institute at Shenzhen · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The precise increase and decrease of hormone ecdysone are critical for accurate development in insects. Most previous works focus on transcriptional activation of ecdysone production; however, little is known about the mechanism of switching off ecdysone biosynthesis after ecdysis. Here, we showed that the precursor microRNA-14 (pre-miR-14) encodes two mature miRNAs in silkworm; both of these two mature miRNAs regulate various genes in the ecdysone-signalling pathway.

Indexed as

3' Untranslated RegionsAnimalsAnimal StructuresBinding SitesBombyxEcdysoneGene Expression RegulationMicroRNAsModels, BiologicalMoltingSignal Transduction3' Untranslated RegionsEcdysoneMicroRNAsdevelopmental synchronyecdysoneMicrornamolting timing

Identifiers

PMID31184522
PMCPMC6693543
OpenAlexW2951375194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.