Evidence map›Paper›PMID 31184514›Full record

ReviewExpert opinion on drug discovery2019

An outlook on using serial femtosecond crystallography in drug discovery.

Alexey Mishin, Anastasiia Gusach, Aleksandra Luginina, Egor Marin, Valentin Borshchevskiy, Vadim Cherezov

Open access · greenAbstract readReview
In one paragraph

Review in Expert opinion on drug discovery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. GPCRs as key regulators in wound healing.Frontiers in cell and developmental biology · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. MicroED structure of the human adenosine receptor determined from a single nanocrystal in LCP.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  8. Article
  9. Article
  10. RCSB Protein Data Bank: Enabling biomedical research and drug discovery.Protein science : a publication of the Protein Society · 2020
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alexey Mishina Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.
Anastasiia Gusacha Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.
Aleksandra Lugininaa Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.
Egor Marina Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.
Valentin Borshchevskiya Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.
Vadim Cherezova Research Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology , Dolgoprudny , Russia.ORCID 0000-0002-5265-3914
Moscow Institute of Physics and Technology · RUUniversity of Southern California · US

Funding

Structural Biology Of G Protein-Coupled ReceptorsR35GM127086 · NIGMS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Vadim Cherezov · 2018 to 2026
$3.6M
NIGMS NIH HHS R35 GM127086
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LasersAnimalsCrystallographyCrystallography, X-RayDrug DevelopmentDrug DiscoveryHigh-Throughput Screening AssaysHumansStructure-Activity RelationshipG Protein Coupled Receptor (GPCR)Lipidic Cubic Phase (LCP)membrane proteinSerial Femtosecond Crystallography (SFX)structure based drug discovery (SBDD)X-ray Free Electron Laser (XFEL)

Identifiers

PMID31184514
PMCPMC6687307
OpenAlexW2950373018

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.