ArticleJournal of the American Chemical Society2019
Ni-Catalyzed Arylboration of Unactivated Alkenes: Scope and Mechanistic Studies.
Article in Journal of the American Chemical Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Practical Ni-Catalyzed Synthesis of Allylic Boronates.ACS omega · 2026Article
- Diverse Synthesis of C-Glycosides by Stereoselective Ni-Catalyzed Carboboration of Glycals.Journal of the American Chemical Society · 2024Article
- Ni-Catalyzed 1,1- and 1,3-Aminoboration of Unactivated Alkenes.Journal of the American Chemical Society · 2023Article
- Three-Component Cross-Electrophile Coupling: Regioselective Electrochemical Dialkylation of Alkenes.Journal of the American Chemical Society · 2023Article
- Ligand Control in Co-Catalyzed Regio- and Enantioselective Hydroboration: Homoallyl Secondary Boronates via Uncommon 4,3-Hydroboration of 1,3-Dienes.Journal of the American Chemical Society · 2023Article
- Chemical insights into the synthetic chemistry of five-membered saturated heterocycles-a transition metal-catalyzed approach.Frontiers in chemistry · 2023Review
- Arylboration of Enecarbamates for the Synthesis of Borylated Saturated N-Heterocycles.Angewandte Chemie (International ed. in English) · 2022Article
- Copper-Catalyzed Coupling of Alkyl Vicinal Bis(boronic Esters) to an Array of Electrophiles.Journal of the American Chemical Society · 2022Article
- Diastereodivergent Synthesis of Cyclopentyl Boronic Esters Bearing Contiguous Fully Substituted Stereocenters.Angewandte Chemie (International ed. in English) · 2022Article
- Directed, nickel-catalyzed 1,2-alkylsulfenylation of alkenyl carbonyl compounds.Chemical science · 2022Article
- Lewis Acid-Catalyzed Halonium Generation for Morpholine Synthesis and Claisen Rearrangement.The Journal of organic chemistry · 2022Article
- Cooperative Pd/Cu Catalysis for Alkene Arylboration: Opportunities for Divergent Reactivity.ACS catalysis · 2022Article
- Catalytic Arylboration of Spirocyclic Cyclobutenes: Rapid Access to Highly Substituted Spiro[3.n]alkanes.ACS catalysis · 2021Article
- Nickel-catalyzed enantioselective 1,2-vinylboration of styrenes.Chemical science · 2021Article
- Chiral Hypervalent Iodine Catalysis Enables an Unusual Regiodivergent Intermolecular Olefin Aminooxygenation.JACS Au · 2021Article
- Bimetallic Cooperative Catalysis for Decarbonylative Heteroarylation of Carboxylic Acids via C-O/C-H Coupling.Angewandte Chemie (International ed. in English) · 2021Article
- Halonium Catalysis: An Underutilized and Underexplored Catalytic Concept in Olefin Functionalizations.Synlett : accounts and rapid communications in synthetic organic chemistry · 2021Article
- Construction of congested CspChemical science · 2021Article
- Three-Component Ni-Catalyzed Silylacylation of Alkenes.ACS catalysis · 2021Article
- Mechanism-Based Design of an Amide-Directed Ni-Catalyzed Arylboration of Cyclopentene Derivatives.Organic letters · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
A method for the Ni-catalyzed arylboration of unactivated monosubstituted, 1,1-disubstituted, and trisubstituted alkenes is disclosed. The reaction is notable in that it converts highly substituted alkenes, aryl bromides, and diboron reagents to products that contain a quaternary carbon and a synthetically versatile carbon-boron bond with control of stereoselectivity and regioselectivity. In addition, the method is demonstrated to be useful for the synthesis of saturated nitrogen heterocycles, which are important motifs in pharmaceutical compounds. Finally, due to the unusual reactivity demonstrated, the mechanistic details of the reaction were studied with both computational and experimental techniques.
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