ArticleSurgical endoscopy2020
Multicenter collaborative retrospective evaluation of peroral endoscopic myotomy for esophageal achalasia: analysis of data from more than 1300 patients at eight facilities in Japan.
Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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Who cites it
18 citing papers in PubMed, 70 citations in OpenAlex.
- Incidence and Predictors of Reflux Esophagitis Following Per-oral Endoscopic Myotomy: A Two-Year Prospective Study.Digestive diseases and sciences · 2026Article
- Article
- Peroral endoscopic myotomy in children with achalasia: A review of the literature.World journal of gastrointestinal endoscopy · 2025Review
- Peroral endoscopic myotomy in spastic esophageal disorders: Clinical outcomes and optimal approaches.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025Article
- An "esophageal rosette" sign is useful for predicting favorable outcomes in peroral endoscopic myotomy for esophageal achalasia.Esophagus : official journal of the Japan Esophageal Society · 2025Article
- The safety and efficacy of endoscopic approaches for the management of Zenker's diverticulum: a multicentre retrospective study.Surgical endoscopy · 2024Article
- Role of endoscopy in patients with achalasia.Clinical endoscopy · 2023Review
- Esophageal diverticula: from diagnosis to therapeutic management-narrative review.Journal of thoracic disease · 2023Review
- Periprocedural safety profile of peroral endoscopic myotomy (POEM)-a retrospective analysis of adverse events according to two different classifications.Surgical endoscopy · 2023Article
- Updates in the Field of Submucosal Endoscopy.Life (Basel, Switzerland) · 2022Review
- Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea.Journal of neurogastroenterology and motility · 2022Article
- Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study.Gastroenterology research and practice · 2022Article
- Double tunnel technique reduces technical failure during POEM in cases with severe submucosal fibrosis.Endoscopy international open · 2021Article
- A Narrative Review of update in per oral endoscopic myotomy (POEM) and endoscopic esophageal surgery.Annals of translational medicine · 2021Review
- Peroral Endoscopic Myotomy for Esophageal Motility Disorders.Clinical endoscopy · 2020Article
- Peroral endoscopic myotomy for management of gastrointestinal motility disorder.World journal of clinical cases · 2020Review
- Large Postperoral Endoscopic Myotomy Capnomediastinum and Capnoperitoneum: A Benign Entity.Journal of the Canadian Association of Gastroenterology · 2020Article
- Effect and safety of mark-guidedWorld journal of gastroenterology · 2020Article
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeroral endoscopic myotomy (POEM) is a novel, minimally invasive treatment for esophageal achalasia. We retrospectively examined and evaluated the results following POEM to verify the technique's efficacy and safety.
methodsWe retrospectively analyzed data for patients who underwent POEM at eight Japanese facilities between September 2008 and October 2015. Pre- and postoperative assessments 3 months and 1 year after POEM included patient interviews, endoscopy, and manometry.
resultsA total of 1346 patients underwent POEM during the study period. Achalasia was the straight type in 1105 patients (82%) and the sigmoid type in 241 patients (18%). The average patient age was 47.2 years (range 3-95 years); 617 patients (46%) were men and 729 (54%) were women. Previous treatment included balloon dilatation in 381 patients (28%) and Heller-Dor operation in 43 patients (3%). The average operation time was 99.6 min. The mean length of the myotomy in the esophageal body was 10.8 cm, and the myotomy extended into the stomach a mean of 2.8 cm. The response rate (Eckardt score ≤ 3) was 95.1% 3 months postoperatively and 94.7% 1 year postoperatively. We noted 50 adverse events (3.7%) of Clavien-Dindo classification grade ≤ IIIa, and all resolved with conservative treatment. There were no Clavien-Dindo classification grade ≥ IIIb adverse events. After POEM, erosive esophagitis according to the Los Angeles classification was absent in 37% of the patients, grade A in 33%, B in 24%, C in 6%, and D in 0.2%. Symptomatic gastroesophageal reflux disease after POEM was confirmed in 14.8% of the patients; both erosive esophagitis and symptomatic gastroesophageal reflux disease responded to treatment with a proton-pump inhibitor.
conclusionOur results confirmed the safety and efficacy of POEM in a large patient series and support POEM as the first-line and standard treatment for esophageal achalasia.
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