ArticleMikrochimica acta2019
Simultaneous amperometric immunosensing of the metastasis-related biomarkers IL-13Rα2 and CDH-17 by using grafted screen-printed electrodes and a composite prepared from quantum dots and carbon nanotubes for signal amplification.
Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- Graphene Quantum Dots for Glioblastoma Treatment and Detection-Systematic Review.Molecules (Basel, Switzerland) · 2025Pooled it
- Metal Nanoparticles and Carbon-Based Nanomaterials for Improved Performances of Electrochemical (Bio)Sensors with Biomedical Applications.Materials (Basel, Switzerland) · 2021Review
- Combination of ultrathin micro-patterned MXene and PEDOT: Poly(styrenesulfonate) enables organic electrochemical transistor for amperometric determination of survivin protein in children osteosarcoma.Mikrochimica acta · 2021Article
- Review
- Revisiting Electrochemical Biosensing in the 21st Century Society for Inflammatory Cytokines Involved in Autoimmune, Neurodegenerative, Cardiac, Viral and Cancer Diseases.Sensors (Basel, Switzerland) · 2020Review
- Multimodal/Multifunctional Nanomaterials in (Bio)electrochemistry: Now and in the Coming Decade.Nanomaterials (Basel, Switzerland) · 2020Review
- Review
- Nanozymes in electrochemical affinity biosensing.Mikrochimica acta · 2020Review
- Electrochemical Biosensors for Determination of Colorectal Tumor Biomarkers.Micromachines · 2020Review
- Carbon nanotubes in electrochemical, colorimetric, and fluorimetric immunosensors and immunoassays: a review.Mikrochimica acta · 2020Review
- Applications of Graphene Quantum Dots in Biomedical Sensors.Sensors (Basel, Switzerland) · 2020Review
- Multiplexed Immunosensors and Immunoarrays.Analytical chemistry · 2020Review
- Multiplexed monitoring of a novel autoantibody diagnostic signature of colorectal cancer using HaloTag technology-based electrochemical immunosensing platform.Theranostics · 2020Article
- Graphene Quantum Dot-Based Electrochemical Immunosensors for Biomedical Applications.Materials (Basel, Switzerland) · 2019Review
- Carbon Dots and Graphene Quantum Dots in Electrochemical Biosensing.Nanomaterials (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
This paper describes a dual electrochemical immunoassay for the simultaneous determination of IL-13Rα2 and CDH-17, two biomarkers of emerging relevance in metastatic processes. The sandwich assay uses a screen-printed dual carbon electrode that was electrochemically grafted with p-aminobenzoic acid to allow the covalent immobilization of capture antibodies. A hybrid composed of graphene quantum dots (GQDs) and multiwalled carbon nanotubes (MWCNTs) act as nanocarriers for the detection antibodies and horseradish peroxidase. The use of this hybrid material considerably improves the assay (in comparison to the use of MWCNTs) due to the peroxidase mimicking activity of the GQDs. The method works at a low working potential (0.20 V vs. Ag pseudo-reference electrode) and thus is not readily interfered by unknown electroactive species. The dual immunoassay allows for the selective determination of both biomarkers with LOD values of 1.4 (IL-13sRα2) and 0.03 ng mL
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Registered trials
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