Evidence map›Paper›PMID 31183512›Full record

ArticleCurrent genetics2020

Functional analysis of the exocyst subunit BcExo70 in Botrytis cinerea.

Wenqing Guan, Juan Feng, Rongxia Wang, Zhiwei Ma, Weixia Wang, Kun Wang, Tingheng Zhu

Abstract read
PubMed Publisher
In one paragraph

Article in Current genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Emerging Roles of Exocyst Complex in Fungi: A Review.Journal of fungi (Basel, Switzerland) · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Destructive Fungal PathogenPathogens (Basel, Switzerland) · 2020
    Review
  11. Exocyst subunitJournal of biosciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Wenqing GuanCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Juan FengTaizhou Vocational College of Science and Technology, Taizhou, Zhejiang, China.
Rongxia WangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Zhiwei MaCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China.
Weixia WangState Key Lab of Rice Biology, China National Rice Research Institute, Hangzhou, Zhejiang, China. weixwang74@126.com.
Kun WangCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China. jekiwk@zjut.edu.cn.
Tingheng ZhuCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, Zhejiang, China. thzhu@zjut.edu.cn.
Zhejiang University of Technology · CNChina National Rice Research Institute · CNTaizhou Vocational and Technical College · CN

Funding

Natural Science Foundation of Zhejiang Province LY18C140005
6 · The paper itself

Abstract

Botrytis cinerea is one of the most important saprophytic plant pathogenic fungi. The exocyst complex and exocytosis was demonstrated to be involved in fungal development and plant infection. Here, we investigated the function of an exocyst subunit gene Bcexo70 in B. cinerea. The results show that knockout of the Bcexo70 gene significantly reduced the fungal growth and hindered the production of conidia and sclerotia. The Bcexo70 deletion strains showed a severe decrease in virulence toward tomato leaves and reduced secretion of cell wall-degrading enzyme. Confocal and electronic microscopic observation showed that the vesicles in the Bcexo70 mutants were enlarged and scattered in the cytoplasm compared to the regular distribution in the hyphal tip in wild-type strain. This study showed that the exocyst gene Bcexo70 is crucial for fungal growth, conidiation and pathogenicity in B. cinerea.

Indexed as

ExocytosisBiomarkersBotrytisCell-Derived MicroparticlesCell MembraneGene Knockdown TechniquesHomologous RecombinationProtoplastsSequence DeletionSpores, FungalVesicular Transport ProteinsBiomarkersVesicular Transport ProteinsBotrytis cinereaexo70ExocystPathogenicityVesicle

Identifiers

PMID31183512
OpenAlexW2949891424

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.