Evidence map›Paper›PMID 31183394›Full record

ArticleJournal of immunology research2019

New Insights on the Adjuvant Properties of the

Olga S Koutsoni, Mourad Barhoumi, Ikram Guizani, Eleni Dotsika

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Frontiers in immunology · 2026
    Article
  2. Annexin A1 downregulatesFrontiers in immunology · 2025
    Article
  3. Article
  4. A Chimera of Th1 Stimulatory Proteins ofBioMed research international · 2021
    Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Olga S KoutsoniLaboratory of Cellular Immunology, Department of Microbiology, Hellenic Pasteur Institute, 127 Vass Sofias Av, 11521 Athens, Greece.ORCID 0000-0001-7046-0481
Mourad BarhoumiLaboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis/Université de Tunis el Manar, 13 Place Pasteur, BP 74, 1002 Tunis-Belvédère, Tunisia.ORCID 0000-0002-2586-3166
Ikram GuizaniLaboratory of Molecular Epidemiology and Experimental Pathology, Institut Pasteur de Tunis/Université de Tunis el Manar, 13 Place Pasteur, BP 74, 1002 Tunis-Belvédère, Tunisia.
Eleni DotsikaLaboratory of Cellular Immunology, Department of Microbiology, Hellenic Pasteur Institute, 127 Vass Sofias Av, 11521 Athens, Greece.ORCID 0000-0001-9264-6965
Tunis University · TNNational and Kapodistrian University of Athens · GRPasteur Hellenic Institute · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is the most effective tool against infectious diseases. Subunit vaccines are safer compared to live-attenuated vaccines but are less immunogenic and need to be delivered with an adjuvant. Adjuvants are essential for enhancing vaccine potency by improving humoral and cell-mediated immune responses. Only a limited number of adjuvants are licensed for human vaccines, and their mode of action is still not clear.

Indexed as

Adjuvants, ImmunologicAnimalsB7-1 AntigenB7-2 AntigenCell LineDisease Models, AnimalEukaryotic Initiation FactorsFemaleHumansInflammationInterleukin-1betaLeishmania infantumLeishmaniasis, VisceralMacrophagesMiceMice, Inbred BALB CAdjuvants, ImmunologicB7-1 AntigenB7-2 AntigenEukaryotic Initiation FactorsInterleukin-1betaOvalbuminProtozoan ProteinsTumor Necrosis Factor-alpha

Identifiers

PMID31183394
PMCPMC6515109
OpenAlexW2942804264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.