Evidence map›Paper›PMID 31183392›Full record

ArticleJournal of immunology research2019

Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome.

D E Martínez-Fernández, J R Padilla-Gutiérrez, F Casillas-Muñoz, Emmanuel Valdés-Alvarado, Brenda Parra-Reyna, Maricela Aceves-Ramírez, J F Muñoz-Valle, U Zalapa Flores, J C Chávez Herrera, Y Valle

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

D E Martínez-FernándezInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.
J R Padilla-GutiérrezInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.ORCID 0000-0002-0240-2797
F Casillas-MuñozInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.
Emmanuel Valdés-AlvaradoInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.ORCID 0000-0001-6810-9203
Brenda Parra-ReynaInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.
Maricela Aceves-RamírezInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.
J F Muñoz-ValleInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.ORCID 0000-0002-2272-9260
U Zalapa FloresEspecialidad en Cardiología, Unidad Médica de Alta Especialidad, Centro Médico Nacional de Occidente (CMNO), Departamento de Cardiología, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico.
J C Chávez HerreraEspecialidad en Cardiología, Unidad Médica de Alta Especialidad, Centro Médico Nacional de Occidente (CMNO), Departamento de Cardiología, Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico.
Y ValleInstituto de Investigación en Ciencias Biomédicas (IICB), Centro Universitario de Ciencias de la Salud (CUCS), Universidad de Guadalajara (UdeG), Sierra Mojada #950, Colonia Independencia, C.P, 44340 Guadalajara, Jalisco, Mexico.ORCID 0000-0002-4940-022X
Universidad de Guadalajara · MXMexican Social Security Institute · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary syndrome (ACS) can be triggered by the presence of inflammatory factors which promote the activation of immune cells by costimulatory molecules such as CD40 and its ligand CD40L. Environmental and genetic factors are involved in the etiology of the ACS. The aim of this study was to explore the gene and protein expression associated with

Indexed as

GenotypeAcute Coronary SyndromeAgedBiomarkersCD40 AntigensCD40 LigandFemaleGene FrequencyGenetic Association StudiesGenetic Predisposition to DiseaseHumansMaleMiddle AgedPolymorphism, Single NucleotideRisk FactorsRNA, MessengerBiomarkersCD40 AntigensCD40 LigandRNA, Messenger

Identifiers

PMID31183392
PMCPMC6515173
OpenAlexW2943722240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.