Evidence map›Paper›PMID 31183385›Full record

ArticleJournal of immunology research2019

IL-21 Expands HIV-1-Specific CD8

Kang Wu, Shaoying Zhang, Xu Zhang, Xinghua Li, Zhongsi Hong, Fei Yu, Bingfeng Liu, Ting Pan, Zhaofeng Huang, Xiao-Ping Tang and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Kang WuInstitute of Human Virology, China.
Shaoying ZhangNational-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710004, China.
Xu ZhangInstitute of Human Virology, China.
Xinghua LiDepartment of Infectious Diseases, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, 519000, China.
Zhongsi HongDepartment of Infectious Diseases, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, 519000, China.
Fei YuInstitute of Human Virology, China.
Bingfeng LiuInstitute of Human Virology, China.
Ting PanInstitute of Human Virology, China.
Zhaofeng HuangInstitute of Human Virology, China.ORCID 0000-0003-4367-6943
Xiao-Ping TangDepartment of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510060, China.
Weiping CaiDepartment of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510060, China.
Jinyu XiaDepartment of Infectious Diseases, Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, 519000, China.
Xuefeng LiInstitute of Human Virology, China.ORCID 0000-0001-8146-8374
Hui ZhangInstitute of Human Virology, China.
Yiwen ZhangInstitute of Human Virology, China.ORCID 0000-0002-5232-0335
Linghua LiDepartment of Infectious Diseases, Guangzhou Eighth People's Hospital, Guangzhou Medical University, Guangzhou, 510060, China.ORCID 0000-0001-5711-8681
Ministry of Education of the People's Republic of China · CNGuangzhou Eighth People's Hospital · CNSun Yat-sen University · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the existence of viral reservoirs, the rebound of human immunodeficiency virus type 1 (HIV-1) viremia can occur within weeks after discontinuing combined antiretroviral therapy. Immunotherapy could potentially be applied to eradicate reactivated HIV-1 in latently infected CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCells, CulturedCohort StudiesEpitopesHIV-1HIV AntigensHIV InfectionsHumansImmunologic MemoryInterferon-gammaInterleukin-15Interleukin-21InterleukinsLymphocyte ActivationVirus ReplicationEpitopesHIV AntigensInterferon-gammaInterleukin-15Interleukin-21Interleukins

Identifiers

PMID31183385
PMCPMC6515191
OpenAlexW2943062978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.