ArticleBioMed research international2019
Bioinformatics Analysis of Gene Expression Profiles of Sex Differences in Ischemic Stroke.
Article in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- Enhancement of adipose stem cell quality via Cu-MON: Transcriptome and bioinformatics analysis of normal and diabetic stem cells.FASEB bioAdvances · 2025Article
- Bioinformatics approaches for studying molecular sex differences in complex diseases.Briefings in bioinformatics · 2024Review
- Sex-Dependency of T Cell-Induced Salt-Sensitive Hypertension and Kidney Damage.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Identification of hypoxia-related genes and exploration of their relationship with immune cells in ischemic stroke.Scientific reports · 2023Article
- Sex differences in the inflammatory response to stroke.Seminars in immunopathology · 2023Review
- Sex-Specific Immune Responses in Stroke.Stroke · 2022Review
- The Importance of CXCL1 in Physiology and Noncancerous Diseases of Bone, Bone Marrow, Muscle and the Nervous System.International journal of molecular sciences · 2022Review
- Systematic Investigation of the Effect of Powerful Tianma Eucommia Capsule on Ischemic Stroke Using Network Pharmacology.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Differentially Expressed Genes and Their Clinical Significance in Ischaemic Stroke: An In-Silico Study.The Malaysian journal of medical sciences : MJMS · 2020Article
- Sex Difference of Ribosome in Stroke-Induced Peripheral Immunosuppression by Integrated Bioinformatics Analysis.BioMed research international · 2020Article
- Bioinformatic analysis for potential biological processes and key targets of heart failure-related stroke.Journal of Zhejiang University. Science. BArticle
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ischemic stroke (IS) is a complex disease with sex differences in epidemiology, presentations, and outcomes. However, the sex-specific mechanism underlying IS remains unclear. The purpose of this study was to identify key genes contributing to biological differences between sexes. First, we downloaded the gene expression data of GSE22255 from Gene Expression Omnibus (GEO). Differentially expressed genes (DEGs) were identified using R software and related packages. Second, DEGs were separately analyzed by Gene Ontology enrichment and pathways analyses. Third, protein-protein interaction (PPI) network was constructed to further investigate the interactions of DEGs. A total of 123 DEGs were identified between sexes, including 8 upregulated and 115 downregulated genes. In the PPI network, ten key genes were identified, including IL1
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.