ArticleChemical science2019
Diacetyl as a "traceless" visible light photosensitizer in metal-free cross-dehydrogenative coupling reactions.
Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 156 citations in OpenAlex.
- ThebioRxiv : the preprint server for biology · 2026Article
- Minisci Reaction by an MW-Boost: A Simple Protocol for Site-Selective Dehydrogenative Cross-Coupling Between Nitrogen-Aromatics and C(spChemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- CdS Quantum Dot Gels as a Direct Hydrogen Atom Transfer Photocatalyst for C-H Activation.Angewandte Chemie (International ed. in English) · 2024Article
- Chemoselective bond activation by unidirectional and asynchronous PCET using ketone photoredox catalysts.Chemical science · 2023Article
- Base-mediated C-B bond activation of benzylic boronate for the rapid construction of β-silyl/boryl functionalized 1,1-diarylalkanes from aromatic alkenes.Chemical science · 2023Article
- Oxidative Cross Dehydrogenative Coupling ofJournal of the American Chemical Society · 2023Article
- Acceptorless cross-dehydrogenative coupling for C(spCommunications chemistry · 2023Article
- Recent Advances in C-H Functionalisation through Indirect Hydrogen Atom Transfer.Molecules (Basel, Switzerland) · 2023Review
- Discovery and Development of the Enantioselective Minisci Reaction.Accounts of chemical research · 2023Article
- Microwave-accelerated cross-dehydrogenative-coupling (CDC) ofRSC advances · 2023Article
- Resurgence and advancement of photochemical hydrogen atom transfer processes in selective alkane functionalizations.Chemical science · 2023Review
- Metal-free visible-induced C(spRSC advances · 2023Article
- Arylcarboxylation of unactivated alkenes with CONature communications · 2023Article
- Heterogeneous Photocatalysis as a Potent Tool for Organic Synthesis: Cross-Dehydrogenative C-C Coupling ofMolecules (Basel, Switzerland) · 2023Article
- Non-noble metal-catalyzed cross-dehydrogenation coupling (CDC) involving ether α-C(spBeilstein journal of organic chemistry · 2023Review
- Dual role of benzophenone enables a fast and scalable C-4 selective alkylation of pyridines in flow.Chemical science · 2022Article
- Homolytic N-S Bond Cleavage in Vinyl Triflimides Enabled by Triplet-Triplet Energy Transfer.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Biomimetic catalytic aerobic oxidation of C-sp(3)-H bonds under mild conditions using galactose oxidase model compound CuChemical science · 2022Article
- Hydrogen Atom Transfer Driven Enantioselective Minisci Reaction of Alcohols.Angewandte Chemie (International ed. in English) · 2022Article
- A general electron donor-acceptor complex for photoactivation of arenesChemical science · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Minisci alkylation is of prime importance for its applicability in functionalizing diverse heteroarenes, which are core structures in many bioactive compounds. In alkyl radical generation processes, precious metal catalysts, high temperatures and excessive oxidants are generally involved, which lead to sustainability and safety concerns. Herein we report a new strategy using diacetyl (2,3-butanedione) as an abundant, visible light-sensitive and "traceless" hydrogen atom abstractor to achieve metal-free cross-dehydrogenative Minisci alkylation under mild conditions. Mechanistic studies supported hydrogen atom transfer (HAT) between an activated C(sp
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.