Evidence map›Paper›PMID 31183045›Full record

ArticleChemical science2019

A sulfonium tethered peptide ligand rapidly and selectively modifies protein cysteine in vicinity.

Dongyuan Wang, Mengying Yu, Na Liu, Chenshan Lian, Zhanfeng Hou, Rui Wang, Rongtong Zhao, Wenjun Li, Yixiang Jiang, Xiaodong Shi and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 66 citations in OpenAlex.

  1. Development of Dimethylsulfonium Probes for Broad Profiling of Methyllysine Reader Proteins.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Non-symmetric stapling of native peptides.Nature reviews. Chemistry · 2024
    Review
  8. Article
  9. Methodology of stable peptide based on propargylated sulfonium.Biochemistry and biophysics reports · 2023
    Article
  10. Article
  11. Article
  12. Peptide-based covalent inhibitors of protein-protein interactions.Journal of peptide science : an official publication of the European Peptide Society · 2023
    Review
  13. Article
  14. Article
  15. Histidine-specific bioconjugationChemical science · 2022
    Article
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Dongyuan WangState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Mengying YuState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Na LiuState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Chenshan LianState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Zhanfeng HouState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Rui WangDepartment of Biomedical Sciences , City University of Hong Kong , Kowloon , Hong Kong . Email: rwang46@cityu.edu.hk.
Rongtong ZhaoState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Wenjun LiState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Yixiang JiangState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Xiaodong ShiState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.
Shuiming LiCollege of Life Sciences and Oceanography , Shenzhen University , Shenzhen , 518055 , China . Email: shuimingli@szu.edu.cn.
Feng YinState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.ORCID 0000-0001-7407-9047
Zigang LiState Key Laboratory of Chemical Oncogenomics , School of Chemical Biology and Biotechnology , Peking University Shenzhen Graduate School , Shenzhen , 518055 , China . Email: lizg@pkusz.edu.cn ; Email: yinfeng@pkusz.edu.cn.ORCID 0000-0002-4649-1592
Peking University · CNCity University of Hong Kong · HKShenzhen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Significant efforts have been invested to develop site-specific protein modification methodologies in the past two decades. In most cases, a reactive moiety was installed onto ligands with the sole purpose of reacting with specific residues in proteins. Herein, we report a unique peptide macrocyclization method

Identifiers

PMID31183045
PMCPMC6530539
OpenAlexW2923801418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.