Evidence map›Paper›PMID 31183027›Full record

ArticleClinics and practice2019

Non-traumatic splenic rupture in amyloidosis as a rare evolution of multiple myeloma.

Lorenzo Perrone, Lorenzo Gervaso, Eugenia Bosco, Francesco Serra, Erica Quaquarini

Open access · goldAbstract read
In one paragraph

Article in Clinics and practice, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 5 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lorenzo PerroneDepartment of Oncology, Maugeri Clinical and Scientific Institutes (IRCCS), Pavia.
Lorenzo GervasoDepartment of Oncology, Maugeri Clinical and Scientific Institutes (IRCCS), Pavia.
Eugenia BoscoDepartment of Oncology, Maugeri Clinical and Scientific Institutes (IRCCS), Pavia.
Francesco SerraDepartment of Oncology, Maugeri Clinical and Scientific Institutes (IRCCS), Pavia.
Erica QuaquariniDepartment of Oncology, Maugeri Clinical and Scientific Institutes (IRCCS), Pavia.
University of Pavia · ITIstituti Clinici Scientifici Maugeri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a 64-year-old man with a diagnosis of IgG lambda multiple myeloma (MM) symptomatic for bone lesions for which he received autologous stem cell transplant after induction treatment and high-dose melphalan, thalidomide and lenalidomide therapy. Twelve years after the diagnosis, he had an unexpected and acute onset of abdominal pain with signs of hypovolemic shock. A computed tomography scan was immediately performed and demonstrated a splenic rupture. A splenectomy was performed but, a week after, the patient developed an acute respiratory distress syndrome and died. After histological exam of the spleen, non-traumatic spleen rupture due to amyloidosis was our final diagnosis. This event is potentially fatal and rare in patients with MM; clinicians should be aware of this potential course of the disease and monitor patients also for amyloid induced organ damages.

Indexed as

Amyloid light chain amyloidosisMultiple myelomaSplenic rupture

Identifiers

PMID31183027
PMCPMC6536836
OpenAlexW2943865758

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.