Evidence map›Paper›PMID 31182936›Full record

ReviewContrast media & molecular imaging2019

State-of-the-Art Preclinical Photoacoustic Imaging in Oncology: Recent Advances in Cancer Theranostics.

Sara Gargiulo, Sandra Albanese, Marcello Mancini

Abstract readReview
In one paragraph

Review in Contrast media & molecular imaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
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  6. Article
  7. Review
  8. Advances in Photoacoustic Imaging of Breast Cancer.Sensors (Basel, Switzerland) · 2025
    Review
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  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
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  18. Article
  19. Algae: A Robust Living Material Against Cancer.International journal of nanomedicine · 2023
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sara Gargiulo *Institute of Biostructure and Bioimaging of National Council of Research, Naples 80145, Italy.ORCID 0000-0003-1894-1047
Sandra Albanese *Institute of Biostructure and Bioimaging of National Council of Research, Naples 80145, Italy.
Marcello ManciniInstitute of Biostructure and Bioimaging of National Council of Research, Naples 80145, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The optical imaging plays an increasing role in preclinical studies, particularly in cancer biology. The combined ultrasound and optical imaging, named photoacoustic imaging (PAI), is an emerging hybrid technique for real-time molecular imaging in preclinical research and recently expanding into clinical setting. PAI can be performed using endogenous contrast, particularly from oxygenated and deoxygenated hemoglobin and melanin, or exogenous contrast agents, sometimes targeted for specific biomarkers, providing comprehensive morphofunctional and molecular information on tumor microenvironment. Overall, PAI has revealed notable opportunities to improve knowledge on tumor pathophysiology and on the biological mechanisms underlying therapy. The aim of this review is to introduce the principles of PAI and to provide a brief overview of current PAI applications in preclinical research, highlighting also on recent advances in clinical translation for cancer diagnosis, staging, and therapy.

Indexed as

Absorption, RadiationAnimalsBiomarkers, TumorComputer SystemsContrast MediaEarly Detection of CancerEquipment DesignHemoglobinsHumansIndocyanine GreenLasersMacromolecular SubstancesMelaninsMetal NanoparticlesNanotubes, CarbonNeoplasmsBiomarkers, TumorContrast MediaHemoglobinsIndocyanine GreenMacromolecular SubstancesMelaninsNanotubes, Carbon

Identifiers

PMID31182936
PMCPMC6515147

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.