Evidence map›Paper›PMID 31182929›Full record

ArticleInternational journal of biological sciences2019

Taurine Transporter Regulates Adipogenic Differentiation of Human Adipose-Derived Stem Cells through Affecting Wnt/β-catenin Signaling Pathway.

Xiaodan Hou, Zhixue Wang, Fang Ding, Yang He, Pengyuan Wang, Xia Liu, Feng Xu, Jun Wang, Yili Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaodan HouSuzhou Institute of Systems Medicine, Center of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou215123, Jiangsu, China.
Zhixue WangDepartment of Burn and Plastic Surgery, North District of Suzhou Municipal Hospital, Suzhou 215008, Jiangsu, China.
Fang DingSuzhou Institute of Systems Medicine, Center of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou215123, Jiangsu, China.
Yang HeSuzhou Institute of Systems Medicine, Center of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou215123, Jiangsu, China.
Pengyuan WangDepartment of Pharmacology, College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Xia LiuDepartment of Pharmacology, College of Pharmacy, Second Military Medical University, Shanghai 200433, China.
Feng XuDepartment of Emergency, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China.
Jun WangDepartment of Emergency, The First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu Province, China.
Yili YangSuzhou Institute of Systems Medicine, Center of Systems Medicine, Chinese Academy of Medical Sciences, Suzhou215123, Jiangsu, China.
Second Military Medical University · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increased adipocytes are associated with obesity and many human disorders including cancers. To further understand the molecular mechanisms of adipogenesis, transcriptome sequencing was performed to find genes involved in the adipogenic differentiation of human adipose-derived stem cells (hASCs). The mRNA of taurine transporter (TauT, also known as SLC6A6) was found significantly upregulated in hASCs undergoing differentiation. TauT expression was also markedly increased in fat tissues from obese mice induced by high fat diet or genetic mutations (

Indexed as

AdipogenesisAnimalsCell DifferentiationCells, CulturedHumansImmunoblottingMembrane GlycoproteinsMembrane Transport ProteinsMiceReal-Time Polymerase Chain ReactionTaurineTaurine TransportersWnt Signaling PathwayhypotaurineMembrane GlycoproteinsMembrane Transport ProteinsTaurineTaurine Transportersadipogenic differentiationhuman adipose-derived stem cellstaurine transporter

Identifiers

PMID31182929
PMCPMC6535786
OpenAlexW2947144564

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.