Evidence map›Paper›PMID 31182923›Full record

ArticleInternational journal of biological sciences2019

FOXA1 is Prognostic of Triple Negative Breast Cancers by Transcriptionally Suppressing

Xiaofeng Dai, Hongye Cheng, Xiao Chen, Ting Li, Jia Zhang, Guoyin Jin, Dongyan Cai, Zhaohui Huang

Open access · goldAbstract read
In one paragraph

Article in International journal of biological sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. European journal of breast health · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. IAPP blocks anti-breast cancer function of CD8Frontiers in immunology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
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  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiaofeng DaiSchool of Biotechnology, Jiangnan University, Wuxi, China.
Hongye ChengSchool of Biotechnology, Jiangnan University, Wuxi, China.
Xiao ChenSchool of Biotechnology, Jiangnan University, Wuxi, China.
Ting LiSchool of Biotechnology, Jiangnan University, Wuxi, China.
Jia ZhangWuxi School of Medicine, Jiangnan University, Wuxi, China.
Guoyin JinWuxi School of Medicine, Jiangnan University, Wuxi, China.
Dongyan CaiWuxi School of Medicine, Jiangnan University, Wuxi, China.
Zhaohui HuangWuxi School of Medicine, Jiangnan University, Wuxi, China.
Jiangnan University · CNWuxi Fourth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Having markers feasible for breast cancer subtyping, especially for triple negative breast cancer identification is crucial for improving the treatment outcome of such cancers. Here we explore the role of FOXA1 in characterizing triple negative breast cancers and the driving mechanisms. Through

Indexed as

ApoptosisBiomarkers, TumorCell Line, TumorCell MovementCell ProliferationCell SurvivalChromatin ImmunoprecipitationFemaleGene Expression Regulation, NeoplasticHepatocyte Nuclear Factor 3-alphaHumansInterleukin-6In Vitro TechniquesPrognosisRNA, Small InterferingSuperoxide DismutaseBiomarkers, TumorFOXA1 protein, humanHepatocyte Nuclear Factor 3-alphaInterleukin-6RNA, Small InterferingSuperoxide DismutaseSuperoxide Dismutase 2breast cancerFOXA1IL6molecular subtypingSOD2triple negative subtype

Identifiers

PMID31182923
PMCPMC6535797
OpenAlexW2947879163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.