Evidence map›Paper›PMID 31182639›Full record

ArticleMolecular and cellular biology2019

DHX33 Interacts with AP-2β To Regulate

Jiuling Wang, Weimin Feng, Zhen Yuan, Jason D Weber, Yandong Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. BCL-2 and BCL-xL in Cancer: Regulation, Function, and Therapeutic Targeting.International journal of molecular sciences · 2026
    Review
  3. Role of DEAD/DEAH-box helicases in immunity, infection and cancers.Cell communication and signaling : CCS · 2025
    Review
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  12. Multi-resolution modeling of a discrete stochastic process identifies causes of cancer.... International Conference on Learning Representations · 2021
    Article
  13. Article
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Jiuling WangDepartment of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Weimin FengDepartment of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China.
Zhen YuanSUSTech/UM Joint Ph.D. Program, Faculty of Health Sciences, University of Macau, Taipa, Macau, China.
Jason D WeberICCE Institute, Department of Medicine, Division of Molecular Oncology, Washington University School of Medicine, St. Louis, Missouri, USA.
Yandong ZhangDepartment of Biology, Southern University of Science and Technology, Shenzhen, Guangdong, China zhangyd@sustech.edu.cn.ORCID 0000-0002-1900-7224
Southern University of Science and Technology · CNUniversity of Macau · MOMolecular Oncology (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The RNA helicase DHX33 has been found to be overexpressed in human cancers, where it promotes cancer development. Previous reports have shown that DHX33 deficiency caused cancer cell apoptosis, but the underlying mechanism remains unknown. In this study, we discovered that DHX33 regulates Bcl-2 family protein expression. In multiple human cancer cell lines, DHX33 was found to stimulate the transcription of

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorCell SurvivalDEAD-box RNA HelicasesFemaleGene Knockdown TechniquesHEK293 CellsHumansMiceMitochondriaPromoter Regions, GeneticProto-Oncogene Proteins c-bcl-2RNA Polymerase IITranscription Factor AP-2BCL2 protein, humanDEAD-box RNA HelicasesDHX33 protein, humanProto-Oncogene Proteins c-bcl-2RNA Polymerase IITFAP2B protein, humanTranscription Factor AP-2apoptosisBADBcl-2Bcl-2 familyDHX33RNA helicase

Identifiers

PMID31182639
PMCPMC6692123
OpenAlexW2969125699

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.