ArticleProceedings of the National Academy of Sciences of the United States of America2019
Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 43 citations in OpenAlex.
- Hippocampal Hap1 down-regulation impairs glucocorticoid receptor nuclear translocation and exacerbates Alzheimer's disease-related neuropathology in APP/PS1 mice.Zoological research · 2026Article
- Adrenarche as a regulator of sensitivity to early adversity.Journal of neuroendocrinology · 2026Review
- An Overview of Depression Pathogenesis: Prevailing Hypotheses and Associated Neurobiological Underpinnings Primarily Evidenced by Rodent Studies.Depression and anxiety · 2026Review
- Article
- Early life stress, literacy and dyslexia: an evolutionary perspective.Brain structure & function · 2024Review
- An Interaction between Brain-Derived Neurotrophic Factor and Stress-Related Glucocorticoids in the Pathophysiology of Alzheimer's Disease.International journal of molecular sciences · 2024Review
- Editorial: Steroid receptors in neuron and glia.Frontiers in endocrinology · 2024Article
- Recent advances in the crosstalk between the brain-derived neurotrophic factor and glucocorticoids.Frontiers in endocrinology · 2024Review
- Genomic glucocorticoid receptor effects guide acute stress-induced delayed anxiety and basolateral amygdala spine plasticity in rats.Neurobiology of stress · 2024Article
- Modulating glucocorticoid receptor actions in physiology and pathology: Insights from coregulators.Pharmacology & therapeutics · 2023Review
- Anxiolytic reversal of classically conditioned / chronic stress-induced gene expression and learning in the Stress Alternatives Model.Behavioural brain research · 2023Article
- Development of a platform to investigate long-term potentiation in human iPSC-derived neuronal networks.Stem cell reports · 2022Article
- The glucocorticoid footprint on the memory engram.Current opinion in endocrine and metabolic research · 2022Article
- Loss of glucocorticoid receptor phosphorylation contributes to cognitive and neurocentric damages of the amyloid-β pathway.Acta neuropathologica communications · 2022Article
- Stress Affects Central Compensation of Neural Responses to Cochlear Synaptopathy in a cGMP-Dependent Way.Frontiers in neuroscience · 2022Article
- Too Blind to See the Elephant? Why Neuroscientists Ought to Be Interested in Tinnitus.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Dual imaging of dendritic spines and mitochondriaNeurobiology of stress · 2021Article
- Postnatal Sox6 Regulates Synaptic Function of Cortical Parvalbumin-Expressing Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Experience and activity-dependent control of glucocorticoid receptors during the stress response in large-scale brain networks.Stress (Amsterdam, Netherlands) · 2021Article
- Prenatal methylmercury exposure and DNA methylation in seven-year-old children in the Seychelles Child Development Study.Environment international · 2021Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Stress can either promote or impair learning and memory. Such opposing effects depend on whether synapses persist or decay after learning. Maintenance of new synapses formed at the time of learning upon neuronal network activation depends on the stress hormone-activated glucocorticoid receptor (GR) and neurotrophic factor release. Whether and how concurrent GR and neurotrophin signaling integrate to modulate synaptic plasticity and learning is not fully understood. Here, we show that deletion of the neurotrophin brain-derived neurotrophic factor (BDNF)-dependent GR-phosphorylation (PO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.