Evidence map›Paper›PMID 31182540›Full record

ArticleAntimicrobial agents and chemotherapy2019

Endocarditis Caused by Highly Penicillin-Resistant Viridans Group Streptococci: Still Room for Vancomycin-Based Regimens.

Juan M Pericàs, Ruvandhi Nathavitharana, Cristina Garcia-de-la-Mària, Carles Falces, Juan Ambrosioni, Manel Almela, Javier García-González, Eduard Quintana, Francesc Marco, Asunción Moreno and 4 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Choice of antimicrobial therapy for infective endocarditis caused by viridans streptococci: an international practice survey.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  2. Article
  3. An Unusual Case ofInfection and drug resistance · 2026
    Article
  4. Review
  5. Article
  6. Review
  7. Clinical isolates ofAntimicrobial agents and chemotherapy · 2024
    Article
  8. Article
  9. Development of High-Level Daptomycin Resistance inAntimicrobial agents and chemotherapy · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Juan M Pericàs *Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Ruvandhi Nathavitharana *Division of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-3544-5021
Cristina Garcia-de-la-Mària *Hospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Carles FalcesHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Juan AmbrosioniHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Manel AlmelaHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Javier García-GonzálezHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Eduard QuintanaHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Francesc MarcoHospital Clinic of Barcelona, ISGlobal, University of Barcelona, Barcelona, Spain.
Asunción MorenoHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Arnold S BayerLA Biomedical Research Institute, Torrance, California, USA.
José M MiróHospital Clínic of Barcelona, Institut d'Investigacions Biomèdiques Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain jmmiro@ub.edu.
Adolf W KarchmerDivision of Infectious Diseases, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Hospital Clínic Endocarditis Study Group
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESBarcelona Institute for Global Health · ESBeth Israel Deaconess Medical Center · USHospital Universitari Arnau de Vilanova · ESUniversity of California, Los Angeles · US

Funding

Mechanisms and Circumvention of Daptomycin Resistance in Streptococcus mitisR01AI130056 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI BAYER, ARNOLD S · 2018 to 2022
$2.4M
NIAID NIH HHS R01 AI130056
6 · The paper itself

Abstract

Optimal treatment options remain unknown for infective endocarditis (IE) caused by penicillin-resistant (PEN-R) viridans group streptococcal (VGS) strains. The aims of this study were to report two cases of highly PEN-R VGS IE, perform a literature review, and evaluate various antibiotic combinations

Indexed as

AdultDrug Resistance, BacterialEndocarditis, BacterialHumansMaleMiddle AgedPenicillinsVancomycinViridans StreptococciPenicillinsVancomycinanimal modelscombination therapyhigh-level penicillin resistanceinfective endocarditisin vitroviridans group streptococci

Identifiers

PMID31182540
PMCPMC6658762
OpenAlexW2950286760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.