ReviewJournal of bacteriology2019
Regulating, Measuring, and Modeling the Viscoelasticity of Bacterial Biofilms
Review in Journal of bacteriology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 51 citations in OpenAlex.
- Sporulation modulates viscoelastic development through extracellular matrix restructuring inbioRxiv : the preprint server for biology · 2026Article
- From Broadband to Single-Tone Stimulation: Frequency-Selective Response ofMicroorganisms · 2026Article
- Microbiological and rheological dynamics of mixed biofilms formed by bacteria and eukaryotic virus.Scientific reports · 2026Article
- Stress-hardening behaviour of biofilm streamers.Nature communications · 2025Article
- Resolving spatiotemporal dynamics in bacterial multicellular populations: approaches and challenges.Microbiology and molecular biology reviews : MMBR · 2025Review
- Coacervate Dense Phase Displaces Surface-EstablishedJournal of the American Chemical Society · 2024Article
- Structure-Thermodynamic Relationship of a Polysaccharide Gel (Alginate) as a Function of Water Content and Counterion Type (Na vs Ca).The journal of physical chemistry. B · 2023Article
- An electrogenetic toggle switch model.Microbial biotechnology · 2023Article
- Experimental challenges in determining the rheological properties of bacterial biofilms.Interface focus · 2022Article
- Probing the growth and mechanical properties ofSynthetic and systems biotechnology · 2022Article
- Microrheology of Pseudomonas aeruginosa biofilms grown in wound beds.NPJ biofilms and microbiomes · 2022Article
- A microfluidic platform for characterizing the structure and rheology of biofilm streamers.Soft matter · 2022Article
- Systems view of Bacillus subtilis pellicle development.NPJ biofilms and microbiomes · 2022Article
- The structural role of bacterial eDNA in the formation of biofilm streamers.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Catalase Activity is Critical for Proteus mirabilis Biofilm Development, Extracellular Polymeric Substance Composition, and Dissemination during Catheter-Associated Urinary Tract Infection.Infection and immunity · 2021Article
- Confinement-induced self-organization in growing bacterial colonies.Science advances · 2021Article
- Biofilm and swarming emergent behaviours controlled through the aid of biophysical understanding and tools.Biochemical Society transactions · 2020Review
- Review
- The Exo-Polysaccharide Component of Extracellular Matrix is Essential for the Viscoelastic Properties ofInternational journal of molecular sciences · 2020Article
- Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy.Science (New York, N.Y.) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biofilms occur in a broad range of environments under heterogeneous physicochemical conditions, such as in bioremediation plants, on surfaces of biomedical implants, and in the lungs of cystic fibrosis patients. In these scenarios, biofilms are subjected to shear forces, but the mechanical integrity of these aggregates often prevents their disruption or dispersal. Biofilms' physical robustness is the result of the multiple biopolymers secreted by constituent microbial cells which are also responsible for numerous biological functions. A better understanding of the role of these biopolymers and their response to dynamic forces is therefore crucial for understanding the interplay between biofilm structure and function. In this paper, we review experimental techniques in rheology, which help quantify the viscoelasticity of biofilms, and modeling approaches from soft matter physics that can assist our understanding of the rheological properties. We describe how these methods could be combined with synthetic biology approaches to control and investigate the effects of secreted polymers on the physical properties of biofilms. We argue that without an integrated approach of the three disciplines, the links between genetics, composition, and interaction of matrix biopolymers and the viscoelastic properties of biofilms will be much harder to uncover.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.