Evidence map›Paper›PMID 31182485›Full record

ArticleThe Journal of biological chemistry2019

High-resolution protein-protein interaction mapping using all-

Simeon S Andrews, Stephanie Schaefer-Ramadan, Nayra M Al-Thani, Ikhlak Ahmed, Yasmin A Mohamoud, Joel A Malek

Abstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  7. Unraveling Protein Interactions between the Temperate Virus Bam35 and ItsInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Simeon S AndrewsDepartment of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha 24144, Qatar.
Stephanie Schaefer-RamadanDepartment of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha 24144, Qatar.ORCID 0000-0001-9650-1472
Nayra M Al-ThaniDepartment of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha 24144, Qatar.
Ikhlak AhmedDepartment of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha 24144, Qatar.
Yasmin A MohamoudGenomics Laboratory, Weill Cornell Medicine in Qatar, Doha 24144, Qatar.
Joel A MalekDepartment of Genetic Medicine, Weill Cornell Medicine in Qatar, Doha 24144, Qatar jom2042@qatar-med.cornell.edu.ORCID 0000-0002-1516-8477

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two-hybrid systems can be used for investigating protein-protein interactions and may provide important information about gene products with unknown function. Despite their success in mapping protein interactions, two-hybrid systems have remained mostly untouched by improvements in next-generation DNA sequencing. The two-hybrid systems rely on one-

Indexed as

High-Throughput Nucleotide SequencingOpen Reading FramesProtein Interaction MappingReproducibility of ResultsTwo-Hybrid System Techniquesfunctional genomicsHelicobacter pyloriinteractomemolecular geneticsnext generation sequencingprotein-protein interactionstructure-functiontwo-hybrid

Identifiers

PMID31182485
PMCPMC6663860

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.