Evidence map›Paper›PMID 31182484›Full record

ArticleThe Journal of biological chemistry2019

Addition of formate dehydrogenase increases the production of renewable alkane from an engineered metabolic pathway.

Juthamas Jaroensuk, Pattarawan Intasian, Cholpisit Kiattisewee, Pobthum Munkajohnpon, Paweenapon Chunthaboon, Supacha Buttranon, Duangthip Trisrivirat, Thanyaporn Wongnate, Somchart Maenpuen, Ruchanok Tinikul and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Synthetic microbes and biocatalyst designs in Thailand.Biotechnology notes (Amsterdam, Netherlands) · 2023
    Review
  4. Insights into cyanobacterial alkane biosynthesis.Journal of industrial microbiology & biotechnology · 2022
    Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Juthamas JaroensukSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.
Pattarawan IntasianSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.
Cholpisit KiattiseweeSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.
Pobthum MunkajohnponSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.
Paweenapon ChunthaboonDepartment of Biochemistry and Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok 14000, Thailand.
Supacha ButtranonSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.
Duangthip TrisriviratDepartment of Biochemistry and Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok 14000, Thailand.
Thanyaporn WongnateSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand.ORCID 0000-0001-5072-9738
Somchart MaenpuenDepartment of Biochemistry, Faculty of Science, Burapha University, Chonburi 20131, Thailand.
Ruchanok TinikulDepartment of Biochemistry and Center for Excellence in Protein and Enzyme Technology, Faculty of Science, Mahidol University, Bangkok 14000, Thailand.
Pimchai ChaiyenSchool of Biomolecular Science and Engineering, Vidyasirimedhi Institute of Science and Technology (VISTEC), Wangchan Valley, Rayong 21210, Thailand pimchai.chaiyen@vistec.ac.th.ORCID 0000-0002-8533-1604
Vidyasirimedhi Institute of Science and Technology · THMahidol University · THBurapha University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An engineered metabolic pathway consisting of reactions that convert fatty acids to aldehydes and eventually alkanes would provide a means to produce biofuels from renewable energy sources. The enzyme aldehyde-deformylating oxygenase (ADO) catalyzes the conversion of aldehydes and oxygen to alkanes and formic acid and uses oxygen and a cellular reductant such as ferredoxin (Fd) as co-substrates. In this report, we aimed to increase ADO-mediated alkane production by converting an unused by-product, formate, to a reductant that can be used by ADO. We achieved this by including the gene (

Indexed as

AlkanesBiofuelsCatalysisCloning, MolecularEscherichia coliFatty AcidsFormate DehydrogenasesMetabolic EngineeringNADOxidation-ReductionXanthobacterAlkanesBiofuelsFatty AcidsFormate DehydrogenasesNADaldehyde deformylating oxygenasealkanebioenergybiofueldehydrogenaseenzymeformate dehydrogenasehydrocarbonmetabolic engineeringrenewablessubstrate inhibitionsynthetic biology

Identifiers

PMID31182484
PMCPMC6663878
OpenAlexW2953012800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.