ArticleSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2019
Drug- and alcohol-related mortality risk after bariatric surgery: evidence from a 7-year prospective multicenter cohort study.
Article in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 22 citations in OpenAlex.
- Ethanol Pharmacokinetics and Alcohol-Related Effects after One-Anastomosis Gastric Bypass: A Prospective before-after Study.Obesity facts · 2026Article
- Drug poisonings following bariatric surgery: Case series report.British journal of clinical pharmacology · 2026Article
- Increased alcohol intake and alcohol use disorder following bariatric surgery: potential mechanisms.Physiology & behavior · 2025Review
- Alcohol use disorder and alcohol-related mortality after metabolic bariatric surgery: prospective controlled cohort study.The British journal of surgery · 2025Article
- Does Prior Bariatric Surgery Predispose to Acetaminophen-Related Acute Liver Failure?Clinical and translational gastroenterology · 2025Article
- Bariatric surgery and alcohol and substance use: A case-control survey study.Drug and alcohol dependence · 2025Article
- Incidence of Substance Use Disorder Following Bariatric Surgery: A Retrospective Cohort Study.Obesity surgery · 2023Article
- Lower survival and higher rates of cirrhosis in patients with ROUX-EN-Y gastric bypass hospitalised with alcohol-associated hepatitis.BMJ open gastroenterology · 2023Article
- The rewarding effects of alcohol after bariatric surgery: do they change and are they associated with pharmacokinetic changes?Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2022Article
- Suicidal thoughts and behaviors in adolescents who underwent bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2020Observational
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIt is unclear whether bariatric surgery affects the risk of drug- and alcohol-related mortality.
objectivesTo compare the observed drug- and alcohol-related mortality rate with age, sex, race, and year-adjusted rates from the general U.S. POPULATION:
settingThe Longitudinal Assessment of Bariatric Surgery-2, a prospective cohort study of 2458 adults who underwent bariatric surgery at 10 U.S. hospitals between April 2006 and April 2009.
methodsParticipants attended presurgery and annual postsurgery assessments for up to 7 years. Drug- and alcohol-related standardized mortality ratios (SMR) comparing the observed post-bariatric surgery mortality rate with the age, sex, race, and year-adjusted expected mortality rate from the general U.S. population, among the entire cohort, and among those who underwent Roux-en-Y gastric bypass (RYGB).
resultsTen deaths related to drug or alcohol use (6 accidental overdose, 1 intentional overdose, 1 intent unknown overdose, and 2 alcoholic liver disease) occurred across 15,616 person-years of follow-up, all among participants who underwent RYGB (n = 1770). The observed mortality rate was significantly higher than expected for all drug- and alcohol-related causes overall (SMR = 2.10, 95% confidence interval = 1.01-3.86, P = .03) and among participants who underwent RYGB (SMR = 2.90, 95% confidence interval = 1.39-5.33, P = .003). The RYGB SMRs were significant for all overdoses (P = .002) and accidental overdoses (P = .01) and in the same direction but nonsignificant for intentional overdoses, intent unknown overdoses, and alcoholic liver disease (P for all ≥. 05).
conclusionsDrug- and alcohol-related mortality is significantly higher than expected in the 7 years after bariatric surgery, specifically after RYGB.
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