Evidence map›Paper›PMID 31181795›Full record

ArticleJournal of clinical medicine2019

Blood Pressure Change from Normal to 2017 ACC/AHA Defined Stage 1 Hypertension and Cardiovascular Risk.

Joung Sik Son, Seulggie Choi, Gyeongsil Lee, Su-Min Jeong, Sung Min Kim, Kyuwoong Kim, Jae Moon Yun, Sang Min Park

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joung Sik SonDepartment of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea. medical114@naver.com.ORCID 0000-0003-2460-3378
Seulggie ChoiDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea. seulggie@gmail.com.
Gyeongsil LeeDepartment of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea. gespino1.gs@gmail.com.
Su-Min JeongDepartment of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea. dpsme@naver.com.
Sung Min KimDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea. ksm9904@naver.com.
Kyuwoong KimDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul 03080, Korea. kwkim238@gmail.com.
Jae Moon YunDepartment of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea. jaemoon2@gmail.com.
Sang Min ParkDepartment of Family Medicine, Seoul National University Hospital, Seoul 03080, Korea. smpark.snuh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this study was to investigate the clinical significance of the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) defined stage 1 hypertension (systolic blood pressure (SBP) 130-139 mmHg or diastolic blood pressure (DBP) 80-89 mmHg), and increase in BP from previously normal BP in Korean adults. We conducted a retrospective analysis of 60,866 participants from a nationally representative claims database. Study subjects had normal BP (SBP < 120 mmHg and DBP < 80 mmHg), no history of anti-hypertensive medication, and cardiovascular disease (CVD) in the first period (2002-2003). The BP change was defined according to the BP difference between the first and second period (2004-2005). We used time-dependent Cox proportional hazards models in order to evaluate the effect of BP elevation on mortality and CVD with a mean follow-up of 7.8 years. Compared to those who maintained normal BP during the second period, participants with BP elevation from normal BP to stage 1 hypertension had a higher risk for CVD (adjusted hazard ratio (aHR) 1.23; 95% confidence interval (CI), 1.08-1.40), and ischemic stroke (aHR 1.32; 95% CI, 1.06-1.64). BP elevation to 2017 ACC/AHA defined elevated BP (SBP 120-129 mmHg and DBP < 80 mmHg) was associated with an increased risk of CVD (aHR 1.26; 95% CI, 1.06-1.50), but stage 1 isolated diastolic hypertension (SBP < 130 and DBP 80-89 mmHg) was not significantly related with CVD risk (aHR 1.12; 95% CI, 0.95-1.31).

Indexed as

2017 ACC/AHA high blood pressure guidelineblood pressure changecardiovascular diseasestage 1 hypertension

Identifiers

PMID31181795
PMCPMC6617274

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.