Evidence map›Paper›PMID 31181726›Full record

ArticleMolecules (Basel, Switzerland)2019

Synthesis and Cytotoxicity of 7,9-

Yu Zhao, Tian-En Wang, Alberto Mills, Federico Gago, Wei-Shuo Fang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu ZhaoState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 2A Nan Wei Road, Beijing 100050, China. zhaoyu8410@126.com.
Tian-En WangState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 2A Nan Wei Road, Beijing 100050, China. wangtianen@imm.ac.cn.
Alberto MillsDepartment of Biomedical Sciences and "Unidad Asociada IQM-CSIC", School of Medicine and Health Sciences, University of Alcalá, E-28805 Alcalá de Henares, Madrid, Spain. albertomillsfernandez@gmail.com.
Federico GagoDepartment of Biomedical Sciences and "Unidad Asociada IQM-CSIC", School of Medicine and Health Sciences, University of Alcalá, E-28805 Alcalá de Henares, Madrid, Spain. federico.gago@uah.es.ORCID 0000-0002-3071-4878
Wei-Shuo FangState Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, 2A Nan Wei Road, Beijing 100050, China. wfang@imm.ac.cn.

Funding

CAMS Innovation Fund for Medical Sciences 2016-I2M-1-01Spanish MEC/MICINN SAF2015-64629-C2-2the Drug Innovation Major Project 2018ZX09711001-001-001 and 2018ZX09711001-001-003
6 · The paper itself

Abstract

A series of novel 7,9-

Indexed as

Bridged-Ring CompoundsCell DeathDocetaxelHeLa CellsHumansMacrocyclic CompoundsMolecular Docking SimulationPaclitaxelStructural Homology, ProteinTaxoidsTubulinBridged-Ring CompoundsDocetaxelIDN 5390Macrocyclic CompoundsPaclitaxelTaxoidsTubulindrug resistanceP-glycoproteintaxoidsβIII-tubulin

Identifiers

PMID31181726
PMCPMC6600541

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.