Evidence map›Paper›PMID 31181713›Full record

ArticleCancers2019

Neoadjuvant Pazopanib Treatment in High-Risk Soft Tissue Sarcoma: A Quantitative Dynamic

Christos Sachpekidis, Ioannis Karampinis, Jens Jakob, Bernd Kasper, Kai Nowak, Lothar Pilz, Ulrike Attenberger, Timo Gaiser, Hans-Günter Derigs, Matthias Schwarzbach and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Quantitative parameters of static imaging and fast kinetics imaging inQuantitative imaging in medicine and surgery · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Christos SachpekidisClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, 69120 Heidelberg, Germany. christos_saxpe@yahoo.gr.
Ioannis KarampinisDivision of Surgical Oncology and Thoracic Surgery, University Medical Center Mannheim, 68167 Mannheim, Germany. Ioannis.Karampinis@umm.de.
Jens JakobDivision of Surgical Oncology and Thoracic Surgery, University Medical Center Mannheim, 68167 Mannheim, Germany. jens.jakob@med.uni-goettingen.de.
Bernd KasperInterdisciplinary Tumor Center Mannheim, Sarcoma Unit, Mannheim University Medical Center, 68167 Mannheim, Germany. bernd.kasper@umm.de.ORCID 0000-0001-8425-8356
Kai NowakDivision of Surgical Oncology and Thoracic Surgery, University Medical Center Mannheim, 68167 Mannheim, Germany. nowakk@me.com.ORCID 0000-0001-7737-3495
Lothar PilzMedical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Lothar.Pilz@medma.uni-heidelberg.de.
Ulrike AttenbergerInstitute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, 68167 Mannheim, Germany. Ulrike.Attenberger@medma.uni-heidelberg.de.
Timo GaiserInstitute of Pathology, University Medical Center Mannheim, 68167 Mannheim, Germany. Timo.Gaiser@umm.de.
Hans-Günter DerigsDepartment of Hematology and Oncology, Klinikum Frankfurt-Hoechst, 65929 Frankfurt am Main, Germany. derigs@klinikumfrankfurt.de.
Matthias SchwarzbachDepartment of Surgery, Klinikum Frankfurt-Hoechst, 65929 Frankfurt am Main, Germany. Matthias.Schwarzbach@KlinikumFrankfurt.de.
Peter HohenbergerDivision of Surgical Oncology and Thoracic Surgery, University Medical Center Mannheim, 68167 Mannheim, Germany. peter.hohenberger@umm.de.
Antonia Dimitrakopoulou-StraussClinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, 69120 Heidelberg, Germany. ads@ads-net.de.ORCID 0000-0003-0338-9472
Ulrich RonellenfitschDivision of Surgical Oncology and Thoracic Surgery, University Medical Center Mannheim, 68167 Mannheim, Germany. Ulrich.Ronellenfitsch@uk-halle.de.ORCID 0000-0003-1107-813X
Heidelberg University · DEGerman Cancer Research Center · DEKlinikum Frankfurt Höchst · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outcome of high-risk soft tissue sarcoma (STS) is poor with radical surgery being the only potentially curative modality. Pazopanib is a multikinase inhibitor approved for the treatment of metastatic STS. Herein, in terms of the German Interdisciplinary Sarcoma Group (GISG-04/NOPASS) trial, we evaluate the potential role of kinetic analysis of fludeoxyglucose F-18 (

Indexed as

dynamic 18F-FDG PET/CTpazopanibsoft tissue sarcoma (STS)SUVtwo-tissue compartment model

Identifiers

PMID31181713
PMCPMC6628287
OpenAlexW2948145442

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.