Evidence map›Paper›PMID 31181667›Full record

ArticleMolecules (Basel, Switzerland)2019

New Heteroleptic Ruthenium(II) Complexes with Sulfamethoxypyridazine and Diimines as Potential Antitumor Agents.

Ariane C C de Melo, Jaime M S V P Santana, Kelen J R C Nunes, Bernardo L Rodrigues, Nathalia Castilho, Philipe Gabriel, Adolfo H Moraes, Mayra de A Marques, Guilherme A P de Oliveira, Ívina P de Souza and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Ariane C C de MeloDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. ariane.quimica@hotmail.com.
Jaime M S V P SantanaDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. jaimemurilosvps@gmail.com.
Kelen J R C NunesDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. cdkelen@hotmail.com.
Bernardo L RodriguesDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. bernardo@qui.ufmg.br.
Nathalia CastilhoDepartment of Biochemistry, Universidade Federal de Santa Catarina, Florianópolis 88040900, SC, Brazil. nathi_zuca@hotmail.com.
Philipe GabrielDepartment of Biochemistry, Universidade Federal de Santa Catarina, Florianópolis 88040900, SC, Brazil. philipe.gabriel.ph@gmail.com.
Adolfo H MoraesDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. adolfo.dq.ufmg@gmail.com.ORCID 0000-0002-3344-4084
Mayra de A MarquesPrograma de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Biologia Estrutural e Bioimagem, Centro Nacional de Ressonância Magnética Nuclear Jiri Jonas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941590, RJ, Brazil. mayra.marques@ymail.com.ORCID 0000-0002-4131-4634
Guilherme A P de OliveiraPrograma de Biologia Estrutural, Instituto de Bioquímica Médica Leopoldo de Meis, Instituto Nacional de Biologia Estrutural e Bioimagem, Centro Nacional de Ressonância Magnética Nuclear Jiri Jonas, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941590, RJ, Brazil. gaugusto@bioqmed.ufrj.br.ORCID 0000-0002-0063-5888
Ívina P de SouzaDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. ivina_paula@yahoo.com.br.
Hernán TerenziDepartment of Biochemistry, Universidade Federal de Santa Catarina, Florianópolis 88040900, SC, Brazil. hterenzi@ccb.ufsc.br.
Elene C Pereira-MaiaDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte 31270-901, MG, Brazil. elene@qui.ufmg.br.ORCID 0000-0003-2699-6232
Universidade Federal de Minas Gerais · BRUniversidade Federal de Santa Catarina · BRUniversidade Federal do Rio de Janeiro · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two new complexes of Ru(II) with mixed ligands were prepared: [Ru(bpy)

Indexed as

Antineoplastic AgentsCircular DichroismHumansK562 CellsLeukemia, Myelogenous, Chronic, BCR-ABL PositiveMolecular StructureOrganometallic CompoundsProto-Oncogene Proteins c-ablRutheniumSpectrometry, Mass, Electrospray Ionizationsrc Homology DomainsSulfamethoxypyridazineX-Ray DiffractionAntineoplastic AgentsOrganometallic CompoundsProto-Oncogene Proteins c-ablRutheniumSulfamethoxypyridazineAbl tyrosine kinasebovine serum albuminDNAruthenium complexessulfonamide

Identifiers

PMID31181667
PMCPMC6600252
OpenAlexW2948614211

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.