Evidence map›Paper›PMID 31181661›Full record

ArticleInternational journal of molecular sciences2019

Petunidin, a B-ring 5'-

Masahiro Nagaoka, Toyonobu Maeda, Sawako Moriwaki, Atsushi Nomura, Yasumasa Kato, Shumpei Niida, Marlena C Kruger, Keiko Suzuki

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Article
  5. Article
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  7. Article
  8. Review
  9. Review
  10. Article
  11. Review
  12. Review
  13. Review
  14. Review
  15. Anthocyanins, Microbiome and Health Benefits in Aging.Molecules (Basel, Switzerland) · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Molecular Mechanisms and Emerging Therapeutics for Osteoporosis.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Masahiro NagaokaDepartment of Pharmacology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. m-nagaoka@den.ohu-u.ac.jp.
Toyonobu MaedaDepartment of Oral Function and Molecular Biology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. t-maeda@den.ohu-u.ac.jp.
Sawako MoriwakiMedical Genome Center, National Center for Geriatrics and Gerontology (NCGG), Aichi 474-8511, Japan. cyawa@ncvc.go.jp.
Atsushi NomuraAKITAYA HONTEN Co., Ltd., Gifu 500-8471, Japan. a-nomura@akitayahonten.co.jp.
Yasumasa KatoDepartment of Oral Function and Molecular Biology, School of Dentistry, Ohu University, Fukushima 963-8611, Japan. yasumasa-kato@umin.ac.jp.ORCID 0000-0003-0192-9324
Shumpei NiidaMedical Genome Center, National Center for Geriatrics and Gerontology (NCGG), Aichi 474-8511, Japan. sniida@ncgg.go.jp.
Marlena C KrugerSchool of Health Sciences, College of Health, Massey University, Palmerston North 4442, New Zealand. M.C.Kruger@massey.ac.nz.ORCID 0000-0002-8646-9672
Keiko SuzukiDepartment of Pharmacology, School of Dentistry, Showa University, Tokyo 142-8555, Japan. kei-suzuki@umin.ac.jp.
Ohu University · JPNational Center for Geriatrics and Gerontology · JPAkita Industrial Technology Center · JPMassey University · NZShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several lines of evidence suggest that oxidative stress is one of the key pathogenic mechanisms of osteoporosis. We aimed to elucidate the bone protective effects of petunidin, one of the most common anthocyanidins, considering its potent antioxidative activity. Petunidin (>5 μg/mL) significantly inhibited osteoclastogenesis and downregulated

Indexed as

OsteogenesisAnimalsAnthocyaninsBone Density Conservation AgentsBone Morphogenetic Protein 2Cancellous BoneFemaleMatrix MetalloproteinasesMiceMice, Inbred C57BLOsteoblastsOsteoporosisRANK LigandRAW 264.7 CellsAnthocyaninsBmp2 protein, mouseBone Density Conservation AgentsBone Morphogenetic Protein 2Matrix MetalloproteinasespetunidinRANK LigandTnfsf11 protein, mouseanthocyaninbone anabolismosteoblastosteoclastosteoporosispetunidin

Identifiers

PMID31181661
PMCPMC6600628
OpenAlexW2948670843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.