Evidence map›Paper›PMID 31181634›Full record

ArticleCells2019

gga-miRNA-18b-3p Inhibits Intramuscular Adipocytes Differentiation in Chicken by Targeting the

Guirong Sun, Fang Li, Xiangfei Ma, Junwei Sun, Ruirui Jiang, Yadong Tian, Ruili Han, Guoxi Li, Yanbin Wang, Zhuanjian Li and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Review
  3. MiRNAs in Poultry Health and Production: Progress and Challenges.Animals : an open access journal from MDPI · 2025
    Review
  4. Review
  5. Non-Coding RNAs in Regulating Fat Deposition in Farm Animals.Animals : an open access journal from MDPI · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Dietary Effect ofFoods (Basel, Switzerland) · 2023
    Article
  16. Article
  17. Biology · 2022
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Guirong SunCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. grsun@henau.edu.cn.
Fang LiCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. fangli0909@126.com.
Xiangfei MaCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. mxf1228@126.com.
Junwei SunCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. jw2013au@126.com.
Ruirui JiangCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. jrrcaas@163.com.
Yadong TianCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. ydtian111@163.com.
Ruili HanCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. Rlhan@126.com.
Guoxi LiCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. liguoxi0914@126.com.
Yanbin WangCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. ybwang2008@126.com.
Zhuanjian LiCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. lizhuanjian@163.com.ORCID 0000-0002-7595-0604
Xiangtao KangCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. xtkang2001@263.net.
Wenting LiCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou 450002, China. liwenting@henau.edu.cn.
Henan Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intramuscular fat (IMF) is the most important evaluating indicator of chicken meat quality, the content of which is positively correlated with tenderness, flavor, and succulence of the meat. Chicken IMF deposition process is regulated by many factors, including genetic, nutrition, and environment. Although large number of omics' studies focused on the IMF deposition process, the molecular mechanism of chicken IMF deposition is still poorly understood. In order to study the role of miRNAs in chicken intramuscular adipogenesis, the intramuscular adipocyte differentiation model (IMF-preadipocytes and IMF-adipocytes) was established and subject to miRNA-Seq. A total of 117 differentially expressed miRNAs between two groups were obtained. Target genes prediction and functional enrichment analysis revealed that eight pathways involved in lipid metabolism related processes, such as fatty acid metabolism and fatty acid elongation. Meanwhile a putative miRNA, gga-miR-18b-3p, was identified be served a function in the intramuscular adipocyte differentiation. Luciferase assay suggested that the gga-miR-18b-3p targeted to the 3'UTR of

Indexed as

Cell Differentiation3' Untranslated RegionsAdipocytesAdipogenesisAnimalsAntagomirsBase SequenceChickensGene LibraryHumansLipid MetabolismLipid PeroxidationMetabolic Networks and PathwaysMicroRNAsRNA InterferenceRNA, Small Interfering3' Untranslated RegionsACOT13 protein, humanAntagomirsMicroRNAsRNA, Small InterferingThiolester HydrolasesACOT13differentiationintramuscular adipocytesmiR-18b-3p

Identifiers

PMID31181634
PMCPMC6627633
OpenAlexW2948588508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.