Evidence map›Paper›PMID 31181610›Full record

ArticleSensors (Basel, Switzerland)2019

Optical Fiber Gratings Immunoassays.

Médéric Loyez, Maxime Lobry, Ruddy Wattiez, Christophe Caucheteur

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Médéric LoyezProteomics and Microbiology Department, Université de Mons, Champ de Mars 6, 7000 Mons, Belgium. mederic.loyez@umons.ac.be.ORCID 0000-0001-8858-7413
Maxime LobryElectromagnetism and Telecom Department, Université de Mons, Bld Dolez 31, 7000 Mons, Belgium. maxime.lobry@umons.ac.be.
Ruddy WattiezProteomics and Microbiology Department, Université de Mons, Champ de Mars 6, 7000 Mons, Belgium. ruddy.wattiez@umons.ac.be.
Christophe CaucheteurElectromagnetism and Telecom Department, Université de Mons, Bld Dolez 31, 7000 Mons, Belgium. christophe.caucheteur@umons.ac.be.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical fibers are of growing interest for biosensing, especially for point-of-care and biomedical assays. Their intrinsic properties bestow them sought-after assets for the detection of low concentrations of analytes. Tilted fiber Bragg gratings (TFBGs) photo-inscribed in the core of telecommunication-grade optical fibers are known to be highly-sensitive refractometers. In this work, we present different strategies to use them for label-free immunoassays. Bare, gold-sputtered, gold-electroless-plated (ELP) and hybrid configurations are biofunctionalized with antibodies, aiming at the detection of cancer biomarkers. We discuss the relative performances of the tested configurations and show that each leads to singular key features, which therefore drives their selection as a function of the target application. The most sensitive configuration presents a limit of detection of 10

Indexed as

AnimalsBiomarkers, TumorBiosensing TechniquesEquipment DesignFiber Optic TechnologyHumansImmunoassayRefractometryBiomarkers, Tumorbiomarkerbiosensingimmunoassaysoptical fiberstilted fiber bragg gratings

Identifiers

PMID31181610
PMCPMC6603621

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.