Evidence map›Paper›PMID 31180995›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2019

A Gap Between Willingness and Uptake: Findings From Mixed Methods Research on HIV Prevention Among Black and Latina Transgender Women.

Tonia Poteat, Andrea Wirtz, Mannat Malik, Erin Cooney, Christopher Cannon, W David Hardy, Renata Arrington-Sanders, Maren Lujan, Thespina Yamanis

Registry-linked trialAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06159582 (eSTEP), which is not on this map. Cited by 86 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06159582 nacompletednot on this mapstarted 2024, after this paper: background citation

eSTEP: An Integrated mHealth Intervention to Engage High-risk Individuals Along the Full PrEP Care Continuum

TypeinterventionalSponsorSan Diego State UniversityRan2024 to 2025Enrolled113ConditionsPre-Exposure Prophylaxis (PrEP)ArmseSTEP, Usual Care
3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  15. Integrating CBPR and Implementation Science to Develop a PrEP-Promotion Intervention for Black Transgender Women.Health education & behavior : the official publication of the Society for Public Health Education · 2026
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26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tonia PoteatDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Andrea WirtzDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Mannat MalikDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Erin CooneyDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD.
Christopher CannonResearch Department, Whitman-Walker Health, Washington, DC.
W David HardyResearch Department, Whitman-Walker Health, Washington, DC.
Renata Arrington-SandersDivision of Pediatrics and Adolescent Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Maren LujanAmerican University, School of International Service, Washington, DC.
Thespina YamanisAmerican University, School of International Service, Washington, DC.

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
SWG 2: Cure Research Scientific Working GroupP30AI117970 · NIAID · GEORGE WASHINGTON UNIVERSITY · PI Italo Mocchetti · 2015 to 2026
$29.6M
NIAID NIH HHS P30 AI094189NIAID NIH HHS P30 AI117970
6 · The paper itself

Abstract

backgroundBlack and Latina transgender women (BLTW) face significant HIV disparities with estimated HIV prevalence up to 50% and annual incidence rates as high as 2.8 per 100 person-years. However, few studies have evaluated the acceptability and uptake of high-impact HIV prevention interventions among BLTW.

settingData collection took place in Baltimore, MD and Washington, DC from May 2015 to May 2017.

methodsThis mixed methods study included quantitative interviewer-administered surveys, key informant interviews, and focus group discussions. Rapid HIV testing followed each survey. Logistic regression models tested associations between legal gender affirmation (ie, desired name and gender marker on identity documents), transgender pride, history of exchange sex, HIV risk perception, and willingness to take pre-exposure prophylaxis (PrEP). Transcripts of qualitative data were coded to identify common themes related to engagement in HIV prevention.

resultsAmong 201 BLTW, 56% tested HIV-positive and 87% had heard of PrEP. Only 18% who had heard of PrEP had ever taken it. Of the 72 self-reported HIV-negative or status-unknown BLTW who had never taken PrEP, 75% were willing to take it. In multivariable analyses, history of exchange sex was associated with willingness to take PrEP, whereas greater HIV knowledge and transgender pride were associated with lower likelihood of willingness to take PrEP. Concern about drug interactions with hormone therapy was the most frequently reported barrier to PrEP uptake.

conclusionsNoting the disconnect between PrEP willingness and uptake among BLTW, HIV prevention programs could bridge this gap by responding to identified access barriers and incorporating community-derived strategies.

Indexed as

Patient Acceptance of Health CarePre-Exposure ProphylaxisTransgender PersonsBlack or African AmericanFemaleHispanic or LatinoHIV InfectionsHumansLogistic ModelsMale

Identifiers

PMID31180995
PMCPMC7807529

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.