Evidence map›Paper›PMID 31180798›Full record

ArticleInnate immunity2019

Expression of human TLR4/myeloid differentiation factor 2 directs an early innate immune response associated with modest increases in bacterial burden during

Amanda Robison, Deann T Snyder, Kelly Christensen, Emily Kimmel, Adeline M Hajjar, Mark A Jutila, Jodi F Hedges

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Innate immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Recent Advances on the Innate Immune Response toFrontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Amanda Robison1 Department of Microbiology and Immunology, Montana State University, USA.
Deann T Snyder1 Department of Microbiology and Immunology, Montana State University, USA.
Kelly Christensen1 Department of Microbiology and Immunology, Montana State University, USA.
Emily Kimmel1 Department of Microbiology and Immunology, Montana State University, USA.
Adeline M Hajjar2 Department of Comparative Medicine, School of Medicine, University of Washington, USA.
Mark A Jutila1 Department of Microbiology and Immunology, Montana State University, USA.
Jodi F Hedges1 Department of Microbiology and Immunology, Montana State University, USA.ORCID 0000-0002-7461-3972
Montana State University · USUniversity of Washington · US

Funding

VIRUSES: FROM PARTICLES TO PROTEOMICSP20RR020185 · NCRR · MONTANA STATE UNIVERSITY - BOZEMAN · PI QUINN, MARK T · 2004 to 2011
$17.0M
CAMs as counter measures against infectious and inflammatory diseaseP01AT004986 · NCCIH · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2008 to 2012
$5.9M
Development of humanized TLR4 SNP mouse modelsR21OD017233 · OD · UNIVERSITY OF WASHINGTON · PI HAJJAR, ADELINE M · 2014 to 2015
$421k
Role of type I IFN and human TLR4 in Coxiella burnetii pathogenesisR21AI117441 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A · 2016 to 2017
$396k
Development of novel, safe and efficacious Coxiella burnetii vaccineR21AI119772 · NIAID · MONTANA STATE UNIVERSITY - BOZEMAN · PI JUTILA, MARK A, RYNDA-APPLE, AGNIESZKA · 2015 to 2016
$396k
NCCIH NIH HHS P01 AT004986NCRR NIH HHS P20 RR020185NIAID NIH HHS R21 AI117441NIAID NIH HHS R21 AI119772NIH HHS R21 OD017233
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Coxiella burnetiiImmunity, InnateAnimalsCytokinesHumansLipopolysaccharidesLungLymphocyte Antigen 96MaleMiceMice, Inbred C57BLMice, TransgenicNeutrophil InfiltrationNeutrophilsQ FeverRadiation ChimeraCytokinesLipopolysaccharidesLY96 protein, humanLymphocyte Antigen 96TLR4 protein, humanToll-Like Receptor 4Chimeracytokinesneutrophil infiltrationtransgenic

Identifiers

PMID31180798
PMCPMC6900644
OpenAlexW2949663435

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.