Evidence map›Paper›PMID 31180366›Full record

ArticleJournal of visualized experiments : JoVE2019

Use of a Linear Accelerator for Conducting In Vitro Radiobiology Experiments.

Jing Hao, Anthony Magnelli, Andrew Godley, Jennifer S Yu

Abstract readVideo-Audio Media
In one paragraph

Article in Journal of visualized experiments : JoVE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing HaoDepartment of Cancer Biology, Cleveland Clinic.
Anthony MagnelliDepartment of Radiation Oncology, Cleveland Clinic.
Andrew GodleyDepartment of Radiation Oncology, Cleveland Clinic.
Jennifer S YuDepartment of Cancer Biology, Cleveland Clinic; Department of Radiation Oncology, Cleveland Clinic; yuj2@ccf.org.

Funding

Selective Targeting of Glioma Stem Cells Through Sema3C/PlexinD1R01NS092641 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI YU, JENNIFER S · 2016 to 2020
$1.7M
Hypoxia Regulates Notch Turnover in Glioma Stem Cells Through VasorinR01NS094199 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI YU, JENNIFER S · 2015 to 2019
$1.7M
NINDS NIH HHS R01 NS092641NINDS NIH HHS R01 NS094199
6 · The paper itself

Abstract

Radiation therapy remains one of the cornerstones of cancer management. For most cancers, it is the most effective, nonsurgical therapy to debulk tumors. Here, we describe a method to irradiate cancer cells with a linear accelerator. The advancement of linear accelerator technology has improved the precision and efficiency of radiation therapy. The biological effects of a wide range of radiation doses and dose rates continue to be an intense area of investigation. Use of linear accelerators can facilitate these studies using clinically relevant doses and dose rates.

Indexed as

HumansParticle AcceleratorsRadiobiologyRadionuclide Imaging

Identifiers

PMID31180366
PMCPMC7071788

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.