ArticleeLife2019
Heterogeneity in surface sensing suggests a division of labor in
Erratum issuedAbstract read
In one paragraph
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 95 papers.
0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed.
- The power of ten: report from the 10th American Society for Microbiology Conference on Biofilms.Journal of bacteriology · 2026Article
- The diabetic wound microenvironment drives emergence and maintenance of CovRS variants in group BInfection and immunity · 2026Article
- Injectisome assembly primesmBio · 2026Article
- c-di-GMP-mediated pause behavior enablesApplied and environmental microbiology · 2026Article
- ThemBio · 2026Article
- Flow-induced bending of flagella restrictsmBio · 2026Article
- Decoding the spatiotemporal heterogeneity of bacterial virulence gene expression using single-cell approaches.Frontiers in microbiology · 2026Review
- Computational model of fractal interface formation in bacterial biofilms.Physical review. E · 2025Article
- Interaction of Bacteria and Fleas, Focusing on the Plague Bacterium-A Review.Microorganisms · 2025Review
- Pseudomonas aeruginosa senses exopolysaccharide trails using type IV pili and adhesins during biofilm formation.Nature microbiology · 2025Article
- Article
- Dissecting microbial communities with single-cell transcriptome analysis.Science (New York, N.Y.) · 2025Review
- T6SS4 is heterogeneously expressed in Yersinia pseudotuberculosis and is a target for transcriptional and post-transcriptional regulation.PLoS pathogens · 2025Article
- Cyclic-di-GMP signalling mutants drive ecological succession and self-generated diversity in experimentally evolved biofilms ofMicrobiology (Reading, England) · 2025Article
- A biofilm-tropiceLife · 2025Article
- DiverseApplied and environmental microbiology · 2025Article
- Flagellum-driven motility enhancesApplied and environmental microbiology · 2025Article
- High-resolution 3D spatial distribution of complex microbial colonies revealed by mass spectrometry imaging.Journal of advanced research · 2025Article
- Dynamic fluid layer around immotile yeast colonies mediates the spread of bacteria.Biophysical journal · 2025Article
- New Insights into the Mediation of Biofilm Formation by Three Core Extracellular Polysaccharide Biosynthesis Pathways inInternational journal of molecular sciences · 2025Article
35 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
13 authors.
Catherine R Armbruster *Department of Microbiology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0003-0795-802X
Calvin K Lee *Department of Bioengineering, University of California, Los Angeles, Los Angeles, United States.ORCID https://orcid.org/0000-0001-6789-0317
Jessica Parker-GilhamDepartment of Microbiology, University of Washington, Seattle, United States.
Jaime de AndaDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, United States.
Aiguo XiaHefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.
Kun ZhaoKey Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin, China.
Keiji MurakamiDepartment of Oral Microbiology, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan.
Boo Shan TsengSchool of Life Sciences, University of Nevada, Las Vegas, United States.ORCID http://orcid.org/0000-0001-7563-0232
Lucas R HoffmanDepartment of Microbiology, University of Washington, Seattle, United States.
Fan JinHefei National Laboratory for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei, China.ORCID https://orcid.org/0000-0003-2313-0388
Caroline S HarwoodDepartment of Microbiology, University of Washington, Seattle, United States.
Gerard Cl WongDepartment of Bioengineering, University of California, Los Angeles, Los Angeles, United States.
Matthew R ParsekDepartment of Microbiology, University of Washington, Seattle, United States.ORCID https://orcid.org/0000-0003-2932-7966
Funding
TRAINING IN MOLECULAR AND CELLULAR BIOLOGYT32GM007270 · NIGMS · UNIVERSITY OF WASHINGTON · PI RAIBLE, DAVID W · 1985 to 2020
$21.0MThe pel exopolysaccharide gene cluster of Pseudomonas aeruginosaR01AI077628 · NIAID · UNIVERSITY OF WASHINGTON · PI MATTHEW R. PARSEK, Daniel J Wozniak · 2009 to 2026
$7.1MPseudomonas aeruginosa sensing and responseR01GM056665 · NIGMS · UNIVERSITY OF WASHINGTON · PI HARWOOD, CAROLINE STONE · 1998 to 2011
$3.0MThe biofilm matrix of P. aeruginosaR01AI143916 · NIAID · UNIVERSITY OF WASHINGTON · PI MACCOSS, MICHAEL, PARSEK, MATTHEW R. · 2019 to 2023
$2.9MSurface sensing, memory, and motility control in biofilm formationR01AI143730 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI O'TOOLE, GEORGE A., WONG, GERARD C · 2019 to 2023
$2.0MPatient-oriented microbiome and advanced culture approaches to identifying the microbial determinants of chronic pediatric diseaseK24HL141669 · NHLBI · UNIVERSITY OF WASHINGTON · PI Lucas R Hoffman · 2018 to 2026
$929kMatrix-associated proteins in biofilm tolerance: Psl and ecotinK22AI121097 · NIAID · UNIVERSITY OF NEVADA LAS VEGAS · PI TSENG, BOO SHAN · 2016 to 2017
$268kNHLBI NIH HHS K24 HL141669NIAID NIH HHS K22 AI121097NIAID NIH HHS R01 AI077628NIAID NIH HHS R01 AI143730NIAID NIH HHS R01 AI143916NIGMS NIH HHS GM56665NIGMS NIH HHS R01 GM056665NIGMS NIH HHS T32 GM007270NIH HHS 1R01AI143730-01NIH HHS 5R01AI077628NIH HHS K22AI121097NIH HHS K24HL141669NIH HHS R01AI143916NIH HHS T32GM007270
Abstract
The second messenger signaling molecule cyclic diguanylate monophosphate (c-di-GMP) drives the transition between planktonic and biofilm growth in many bacterial species.
Indexed as
Bacterial AdhesionBacterial ProteinsBiofilmsCell MembraneCyclic GMPGene Expression Regulation, BacterialPseudomonas aeruginosaQuorum SensingBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPbiofilmc-di-gmpinfectious diseasemicrobiologyPseudomonas aeruginosasurface sensingWsp system
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.