ArticleeLife2019
'Online' integration of sensory and fear memories in the rat medial temporal lobe.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 57 citations in OpenAlex.
- Differential Modulation of Retroactive Emotional Learning on Concrete and Abstract Word Processing.Psychophysiology · 2026Article
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- Projecting neurons from the lateral entorhinal cortex to the basolateral amygdala mediate the encoding of incidental odor-taste associations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Integrating past experiences.eLife · 2025Article
- Article
- The curious case of dopaminergic prediction errors and learning associative information beyond value.Nature reviews. Neuroscience · 2025Review
- Integration of conditioned threat with pre-existing memories.Learning & memory (Cold Spring Harbor, N.Y.) · 2025Article
- Semantic structures facilitate threat memory integration throughout the medial temporal lobe and medial prefrontal cortex.Current biology : CB · 2024Article
- The Basolateral Amygdala: The Core of a Network for Threat Conditioning, Extinction, and Second-Order Threat Conditioning.Biology · 2023Review
- The role of memory in counterfactual valuation.Journal of experimental psychology. General · 2023Article
- Danger Changes the Way the Brain Consolidates Neutral Information; and Does So by Interacting with Processes Involved in the Encoding of That Information.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Article
- Selective engram coreactivation in idling brain inspires implicit learning.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Targeted effects of ketamine on perceptual expectation during mediated learning in rats.Psychopharmacology · 2022Article
- Laboratory models of post-traumatic stress disorder: The elusive bridge to translation.Neuron · 2022Review
- Anterior cingulate neurons signal neutral cue pairings during sensory preconditioning.Current biology : CB · 2022Article
- Understanding Associative Learning Through Higher-Order Conditioning.Frontiers in behavioral neuroscience · 2022Review
- How common is a common error term? The rules that govern associative learning in sensory preconditioning and second-order conditioning.Frontiers in behavioral neuroscience · 2022Review
- Dimensions and mechanisms of memory organization.Neuron · 2021Review
- Memory and decision making interact to shape the value of unchosen options.Nature communications · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
How does a stimulus never associated with danger become frightening? The present study addressed this question using a sensory preconditioning task with rats. In this task, rats integrate a sound-light memory formed in stage 1 with a light-danger memory formed in stage 2, as they show fear when tested with the sound in stage 3. Here we show that this integration occurs 'online' during stage 2: when activity in the region that consolidated the sound-light memory (perirhinal cortex) was inhibited during formation of the light-danger memory, rats no longer showed fear when tested with the sound but continued to fear the light. Thus, fear that accrues to a stimulus paired with danger simultaneously spreads to its past associates, thereby roping those associates into a fear memory network.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.