Evidence map›Paper›PMID 31180060›Full record

ReviewJournal of biosciences2019

Biosynthesis of some organic acids and lipids in industrially important microorganisms is promoted by pyruvate carboxylases.

Shou-Feng Zhao, Zhe Chi, Guang-Lei Liu, Zhong Hu, Long-Fei Wu, Zhen-Ming Chi

Abstract readReview
PubMed
In one paragraph

Review in Journal of biosciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 11 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shou-Feng ZhaoCollege of Marine Life Sciences, Ocean University of China, Yushan Road, No. 5, Qingdao 266003, People's Republic of China.
Zhe Chi
Guang-Lei Liu
Zhong Hu
Long-Fei Wu
Zhen-Ming Chi
Ocean University of China · CNQingdao Municipal Hospital · CNShantou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyruvate carboxylase (Pyc) catalyzes formation of oxaloacetic acid from pyruvic acid by fixing one mole of CO2. Many evidences have confirmed that biosynthesis of some different kinds of organic acids and intracellular and extracellular lipids is driven by Pyc and over-expression of the PYC gene in the industrial microorganisms can promote production of the different kinds of organic acids and intracellular and extracellular lipids. Therefore, the Pyc from different sources is regarded as a key enzyme in microbial biotechnology and is an important target for metabolic engineering of the industrial microbial strains. However, very little is known about the native Pycs and their functions and regulation in the industrial microorganisms.

Indexed as

Gene Expression Regulation, BacterialBacteriaBacterial ProteinsCarbon DioxideDicarboxylic AcidsFungal ProteinsFungiGene ExpressionHumansIndustrial MicrobiologyLipidsMetabolic EngineeringPyruvate CarboxylaseBacterial ProteinsCarbon DioxideDicarboxylic AcidsFungal ProteinsLipidsPyruvate Carboxylase

Identifiers

PMID31180060
OpenAlexW2937124183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.